ID A0A553PWE5_9TELE Unreviewed; 575 AA.
AC A0A553PWE5;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216};
GN ORFNames=DNTS_030975 {ECO:0000313|EMBL:TRY81964.1};
OS Danionella translucida.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danionella.
OX NCBI_TaxID=623744 {ECO:0000313|EMBL:TRY81964.1, ECO:0000313|Proteomes:UP000316079};
RN [1] {ECO:0000313|Proteomes:UP000316079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bolton {ECO:0000313|Proteomes:UP000316079};
RA Kadobianskyi M., Schulze L., Schuelke M., Judkewitz B.;
RT "Hybrid genome assembly and annotation of Danionella translucida.";
RL bioRxiv 0:0-0(2019).
RN [2] {ECO:0000313|EMBL:TRY81964.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bolton {ECO:0000313|EMBL:TRY81964.1};
RC TISSUE=Whole-body {ECO:0000313|EMBL:TRY81964.1};
RA Kadobianskyi M., Schulze L., Schuelke M., Judkewitz B.;
RT "Hybrid genome assembly and annotation of Danionella translucida.";
RL J. ISSAAS 0:0-0(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|RuleBase:RU361216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TRY81964.1}.
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DR EMBL; SRMA01026583; TRY81964.1; -; Genomic_DNA.
DR EMBL; SRMA01026583; TRY81965.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A553PWE5; -.
DR STRING; 623744.A0A553PWE5; -.
DR Proteomes; UP000316079; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:1902475; P:L-alpha-amino acid transmembrane transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR11958:SF102; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR11958; SODIUM/DICARBOXYLATE SYMPORTER-RELATED; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361216};
KW Reference proteome {ECO:0000313|Proteomes:UP000316079};
KW Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|RuleBase:RU361216};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361216};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361216};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361216}.
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 128..150
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 252..271
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 292..313
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 325..351
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 363..384
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 575 AA; 62974 MW; 3FFE3B6601A41C48 CRC64;
MDETRSTSRP ASSQCHSPPP NAWRNMVEYF KNLMHNSISQ KIREWVKDYC KRNGLLTLSV
LAVMSGCVVG FTLRSLNLST QAKIYFSFPG ELLMRMLKML ILPLITSSLM SGLSAMDTKA
SGRLGLLTIT YYLWTTFIAV IVGIVLVLII HPGTGTEKEG HKAGGGPVMT SADALLDLIR
NMIPSNLIEA TFQQYKTELV PNFKSNTKSS QANFVYIMPD YENPKMGHPV FLELTPPPEI
HYKIVPGKSN GMNVLGIVIF SATMGLLLGR MGSRGSPLVN VCLCINECVM KIINAAMWYF
PFGIVFLVAG KILDMHDPAV LAEKLGMYFI TVLAGLFVHG VILLPLFFFL FTRQNPFSYI
RGLLQALVIA LATSSSSATL PITMKCLLEN CHVDRKIARF VLPVGATINM DGTALYEAVA
AIFIAQVNEY ELDFGQLVTI SITATAASIG AAGIPQAGLV TMVIVLTSVG LPPDDISLIV
AIDWILDRFR TMINVLGDAL AAGIMAHLCK KDFQKDIPST TNSERRDTMI SFGNQSVQSF
PTSEAPLLVN RDYIIDVTGD QVIEKPTACY NLCQV
//
