ID A0A553Q892_9TELE Unreviewed; 712 AA.
AC A0A553Q892;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Poly(A)-specific ribonuclease RNA-binding domain-containing protein {ECO:0000259|Pfam:PF08675};
GN ORFNames=DNTS_030205 {ECO:0000313|EMBL:TRY86143.1};
OS Danionella translucida.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danionella.
OX NCBI_TaxID=623744 {ECO:0000313|EMBL:TRY86143.1, ECO:0000313|Proteomes:UP000316079};
RN [1] {ECO:0000313|Proteomes:UP000316079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bolton {ECO:0000313|Proteomes:UP000316079};
RA Kadobianskyi M., Schulze L., Schuelke M., Judkewitz B.;
RT "Hybrid genome assembly and annotation of Danionella translucida.";
RL bioRxiv 0:0-0(2019).
RN [2] {ECO:0000313|EMBL:TRY86143.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bolton {ECO:0000313|EMBL:TRY86143.1};
RC TISSUE=Whole-body {ECO:0000313|EMBL:TRY86143.1};
RA Kadobianskyi M., Schulze L., Schuelke M., Judkewitz B.;
RT "Hybrid genome assembly and annotation of Danionella translucida.";
RL J. ISSAAS 0:0-0(2019).
CC -!- SIMILARITY: Belongs to the CAF1 family.
CC {ECO:0000256|ARBA:ARBA00008372}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TRY86143.1}.
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DR EMBL; SRMA01026244; TRY86134.1; -; Genomic_DNA.
DR EMBL; SRMA01026244; TRY86135.1; -; Genomic_DNA.
DR EMBL; SRMA01026244; TRY86137.1; -; Genomic_DNA.
DR EMBL; SRMA01026244; TRY86138.1; -; Genomic_DNA.
DR EMBL; SRMA01026244; TRY86141.1; -; Genomic_DNA.
DR EMBL; SRMA01026244; TRY86143.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A553Q892; -.
DR Proteomes; UP000316079; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:InterPro.
DR CDD; cd02637; R3H_PARN; 1.
DR CDD; cd12428; RRM_PARN; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR034042; PARN_R3H.
DR InterPro; IPR014789; PolyA-riboNase_RNA-binding.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR006941; RNase_CAF1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR15092; POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1; 1.
DR PANTHER; PTHR15092:SF44; POLY(A)-SPECIFIC RIBONUCLEASE PARN; 1.
DR Pfam; PF04857; CAF1; 2.
DR Pfam; PF08675; RNA_bind; 1.
DR SUPFAM; SSF82708; R3H domain; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000316079}.
FT DOMAIN 501..578
FT /note="Poly(A)-specific ribonuclease RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF08675"
FT REGION 238..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 663..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..261
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 712 AA; 79838 MW; 6EC128246C4BDCC9 CRC64;
MEVTRQTDFK EVLPEVCRAV QEADFISIDG EFTGISDGPS VSALTNGLDT PEERYSKLRK
GAFAAVVVLA GSGSDQMRSF VAIAEEKPVS IVQCRASELC FNSVSLAQTR SAQHPEIVCA
SLAAFRDPLS LASKIHSMNF LLFQFGLCTF RYDQNQAKYV TKAFNFYIFP RPSSRTSPDI
KFICQVCGLL LEVVRGSMFL MKSSSIDFLA SQGFDFNKVF RCGIPYLTHE GEAQLREQYE
ERRSQSNGAG PLSYTPSSGE SVCNVPEEQK EFIRSVEMKV EGLLKNSEQT VDLEPCTGFQ
RKLIYQTLNS KYPKGLHVET LETDKEELND AVGFSTVVRA ISSSGKLVVG HNMLLDVMHT
IHQFCTPLPE ELDDFKEVAM SVFPRLLDTK LMASTQPFKE MIGNTSLAEL HKQLREKPFS
SPATERAEGS RSYDTSTEQL HEAGYDAFIT GLCFISMANQ LGSFLTPPKS HISARSKLLE
PFFNKLFLMR VIDIPYLNMS GPDLQPKRDH VLYVTFPKEW KTSDLYQLFS AFGNIQVSWV
DDTSAFVSLS QTEQVQIAMN TSRYAESYRI QTYSQYLQSR QKHPRSSRKW NDEGWADTSC
PDSNTHTHLQ AVKRSISPSL EDPSTGGERL SWSEYSGVKK IKTDGSCSQA YLADDCDWPR
LPTNEGGASV SLVQPEVEPD EVSSKKSRKH KKRKSDASET LPPVIFDVPQ VW
//
