ID   A0A553R2K5_9TELE        Unreviewed;       197 AA.
AC   A0A553R2K5;
DT   16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=Lens fiber membrane intrinsic protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DNTS_029323 {ECO:0000313|EMBL:TRY96393.1};
OS   Danionella translucida.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danionella.
OX   NCBI_TaxID=623744 {ECO:0000313|EMBL:TRY96393.1, ECO:0000313|Proteomes:UP000316079};
RN   [1] {ECO:0000313|Proteomes:UP000316079}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bolton {ECO:0000313|Proteomes:UP000316079};
RA   Kadobianskyi M., Schulze L., Schuelke M., Judkewitz B.;
RT   "Hybrid genome assembly and annotation of Danionella translucida.";
RL   bioRxiv 0:0-0(2019).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU363088}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363088}.
CC   -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family.
CC       {ECO:0000256|ARBA:ARBA00006864, ECO:0000256|RuleBase:RU363088}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TRY96393.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; SRMA01025300; TRY96393.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A553R2K5; -.
DR   Proteomes; UP000316079; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:InterPro.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR003935; LMIP.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   InterPro; IPR004032; PMP22_EMP_MP20.
DR   PANTHER; PTHR10671; EPITHELIAL MEMBRANE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR10671:SF9; LENS FIBER MEMBRANE INTRINSIC PROTEIN; 1.
DR   Pfam; PF00822; PMP22_Claudin; 1.
DR   PRINTS; PR01453; EPMEMFAMILY.
DR   PRINTS; PR01457; LENSMEMPROT.
DR   PROSITE; PS01221; PMP22_1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363088};
KW   Reference proteome {ECO:0000313|Proteomes:UP000316079};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363088};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363088}.
FT   TRANSMEM        6..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363088"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363088"
FT   TRANSMEM        123..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363088"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363088"
SQ   SEQUENCE   197 AA;  22377 MW;  34245637371BC369 CRC64;
     MYSFMGGGLF CAIVGNILIV VSTATDYWMQ YRLSGSYAHQ GLWRYCMANK CYMQTASIGS
     AKLPWSHKLT TEITGAVLWF VQAYWNATRA FMILSGMACF AGIMAGILSF AHFSAFERFS
     RSFAAGIMFF ISTFFVLLAM AIYTGVTLSF LGKRFGDWRF SWSYILGWVA MLMTFFAGIF
     YMCAHRMYES RRVVGSR
//