ID A0A553R4L3_9TELE Unreviewed; 760 AA.
AC A0A553R4L3;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Band 4.1-like protein 5 {ECO:0000256|ARBA:ARBA00023841};
DE AltName: Full=Erythrocyte membrane protein band 4.1-like 5 {ECO:0000256|ARBA:ARBA00030226};
GN ORFNames=DNTS_027294 {ECO:0000313|EMBL:TRY97110.1};
OS Danionella translucida.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danionella.
OX NCBI_TaxID=623744 {ECO:0000313|EMBL:TRY97110.1, ECO:0000313|Proteomes:UP000316079};
RN [1] {ECO:0000313|Proteomes:UP000316079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bolton {ECO:0000313|Proteomes:UP000316079};
RA Kadobianskyi M., Schulze L., Schuelke M., Judkewitz B.;
RT "Hybrid genome assembly and annotation of Danionella translucida.";
RL bioRxiv 0:0-0(2019).
RN [2] {ECO:0000313|EMBL:TRY97110.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bolton {ECO:0000313|EMBL:TRY97110.1};
RC TISSUE=Whole-body {ECO:0000313|EMBL:TRY97110.1};
RA Kadobianskyi M., Schulze L., Schuelke M., Judkewitz B.;
RT "Hybrid genome assembly and annotation of Danionella translucida.";
RL J. ISSAAS 0:0-0(2019).
CC -!- FUNCTION: Plays a role in the formation and organization of tight
CC junctions during the establishment of polarity in epithelial cells.
CC {ECO:0000256|ARBA:ARBA00023750}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Photoreceptor inner segment
CC {ECO:0000256|ARBA:ARBA00004437}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TRY97110.1}.
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DR EMBL; SRMA01025242; TRY97109.1; -; Genomic_DNA.
DR EMBL; SRMA01025242; TRY97110.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A553R4L3; -.
DR Proteomes; UP000316079; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0001917; C:photoreceptor inner segment; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13186; FERM_C_NBL4_NBL5; 1.
DR CDD; cd17205; FERM_F1_EPB41L5; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF15; BAND 4.1-LIKE PROTEIN 5; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000316079}.
FT DOMAIN 43..321
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 346..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 586..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 760 AA; 84041 MW; 9AA724031BBA5357 CRC64;
MLSFLRRTLG RRSIRKHAEK ARLREAQRAT THIPAAGDSK SIITCRVSLL DGTDVSVDLP
KKAKGAELFE QIMYHLDVVE KDYFGLRFMD SAQVPHWLDV TKSIKKQVKI GPPYCLHMRV
KFYSSEPNNL HEELTRYLFV LQLKQDILSG KLECPFETAV ELAAYALQAE LGDCDPADHG
LDLVSEFRFI PNQTEEMEGA IYNAWKECRG QTPAQAEINY LNKAKWLEMY GVDMHMVKAR
DGNEYSLGLT PTGVLVFEGE TKIGLFFWPK ITRLDFKKCK LTLVVGKEQE HTFVFRMEHP
KACKHLWKCA VEHHAFFRLR GPVQKGSARS GFIRMGSRFR YSGKTEYQTT KANKARRSAS
FERRPSRRYS RRTMLNRGPI KSSDHHNNGV NSNLETKASH ARHPWSCLPV VSSPSTAPCP
MEIETLPRSP GGSQSDKRSM PVVTDLLETC VDEVLRTPVP MVTAEEVASG AAYSTASSVP
DETLSLTEAA ARLKQLEIEQ TPVSVPARTN LNINMNNQED VVKLTEKCLN SVGSSPVLNQ
LKAAEELKSN ILKAQAEAAL KDSRDELGVT PDKNCNLQEA AVRMGGHGVR MGSTSSLPVS
GRSERQESWD VLKPPGLLPH STSSLDEKAD DFLSSATPLS SDPANEAQSS KVKVEDAEVL
PAALSENLID FTDPVPVAPT PKPTITPRWI IPASAPLLSG SFTNGLLDCP AKPSPLHPEV
TAGPSLPQLS HPHNVIASSI VAHPSKEDTH RPKGLLTTEL
//
