ID A0A556TTH9_BAGYA Unreviewed; 674 AA.
AC A0A556TTH9;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 03-MAY-2023, entry version 16.
DE SubName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 {ECO:0000313|EMBL:TSK62644.1};
GN ORFNames=Baya_4772 {ECO:0000313|EMBL:TSK62644.1};
OS Bagarius yarrelli (Goonch) (Bagrus yarrelli).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Sisoridae; Sisorinae; Bagarius.
OX NCBI_TaxID=175774 {ECO:0000313|EMBL:TSK62644.1, ECO:0000313|Proteomes:UP000319801};
RN [1] {ECO:0000313|EMBL:TSK62644.1, ECO:0000313|Proteomes:UP000319801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JWS20170419001 {ECO:0000313|EMBL:TSK62644.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TSK62644.1};
RX PubMed=31274158;
RA Jiang W., Lv Y., Cheng L., Yang K., Chao B., Wang X., Li Y., Pan X.,
RA You X., Zhang Y., Yang J., Li J., Zhang X., Liu S., Sun C., Yang J.,
RA Shi Q.;
RT "Whole-Genome Sequencing of the Giant Devil Catfish, Bagarius yarrelli.";
RL Genome Biol. Evol. 11:2071-2077(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the synaptogyrin family.
CC {ECO:0000256|ARBA:ARBA00010252}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TSK62644.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; VCAZ01000017; TSK62644.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A556TTH9; -.
DR Proteomes; UP000319801; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 2.
DR InterPro; IPR008253; Marvel.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR016579; Synaptogyrin.
DR PANTHER; PTHR10838; SYNAPTOGYRIN; 1.
DR PANTHER; PTHR10838:SF7; SYNAPTOGYRIN-1; 1.
DR Pfam; PF01284; MARVEL; 1.
DR Pfam; PF00481; PP2C; 2.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS51225; MARVEL; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:TSK62644.1};
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000319801};
KW Transferase {ECO:0000313|EMBL:TSK62644.1};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..173
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
FT DOMAIN 284..546
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 196..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 586..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 674 AA; 73409 MW; C2174CD05411811A CRC64;
MEGTAYGAGR AGGAFDPLTF LQQPYTVLRM VSWLFSLVIF GCIANEGYVN RPHEVVEYCV
FNRNQNACNY AVGMGTLAFI CCMAFLALDV YFPQISSVKD RKKVVLADVG VSAFWSFVWF
VGFCFMANQW QVAKPEDNPL KEGADAARAA ITFSFFSIFT WAGQSFLAFQ RFKLGADSAL
FSQDYTDPSQ DAAAAPYSAF TSGDEPESPG GTGSYRQPNG EGVFDESAGY QLTSTPKFTE
RFRILTKFRF RFKMAASRKP LIHSHQSWTD DLPLCQLCGV GTAPNCVYSP DGKSTQMHPN
EDGHFRFSTE SCFLYGVFNG YDGSRVANFV SQCLTAELLL GQLNSNHSDA DIRRILTQGA
MFHQLSPQSQ KIAERLKTLE QEVSGGATAI IALILNNKLY IANVGLDPNR LRQAGIIAGQ
CSLRRIGDYK VKFSYTDIDV LSAAKSKPII AEPEIHGGQS LDGVTGFLLL MSEGLIKALE
SAHGPEQANQ EMVAMVSAEL AQQGNVEAAA QSVVERVKRL HHDAYARQRA GQCSRHEDMT
LLIRTINYPL SDGSLTPTQV SVPYSNSQST SKTSVTLSLV MPAQGTLTNG TNTASTLEGG
TPTPGQSPTA TLQSNTHTQS SSSSSGDGSL FRQRASQAAQ PDETGRVPPY VDFTQFYQMW
GTEHSEGMRG PGPQ
//
