ID A0A558DNC0_9PSEU Unreviewed; 382 AA.
AC A0A558DNC0;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=ACR3 family arsenite efflux transporter {ECO:0000313|EMBL:TVT62511.1};
GN Name=arsB {ECO:0000313|EMBL:TVT62511.1};
GN ORFNames=FNH05_00885 {ECO:0000313|EMBL:TVT62511.1};
OS Amycolatopsis rhizosphaerae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=2053003 {ECO:0000313|EMBL:TVT62511.1, ECO:0000313|Proteomes:UP000320011};
RN [1] {ECO:0000313|EMBL:TVT62511.1, ECO:0000313|Proteomes:UP000320011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TBRC 6029 {ECO:0000313|EMBL:TVT62511.1,
RC ECO:0000313|Proteomes:UP000320011};
RA Duangmal K., Teo W.F.A.;
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TVT62511.1, ECO:0000313|Proteomes:UP000320011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TBRC 6029 {ECO:0000313|EMBL:TVT62511.1,
RC ECO:0000313|Proteomes:UP000320011};
RA Srisuk N.;
RT "Amycolatopsis acidicola sp. nov., isolated from peat swamp forest soil.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|PIRNR:PIRNR005508}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|PIRNR:PIRNR005508}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC family. {ECO:0000256|ARBA:ARBA00010110, ECO:0000256|PIRNR:PIRNR005508}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TVT62511.1}.
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DR EMBL; VJWX01000004; TVT62511.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A558DNC0; -.
DR OrthoDB; 3420410at2; -.
DR Proteomes; UP000320011; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR004706; Arsenical-R_Acr3.
DR InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR NCBIfam; TIGR00832; acr3; 1.
DR PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR Pfam; PF01758; SBF; 1.
DR PIRSF; PIRSF005508; Acr3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR005508};
KW Membrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000320011};
KW Transmembrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|PIRNR:PIRNR005508,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR005508}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 351..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 41746 MW; B617125681718BA8 CRC64;
MKRLSTLDRF LPVWIGAAMV AGVLLGRFVP GLQRVLDAVK VGDVSLPIAL GLLLMMYPVL
AKVRYDKLDT VTRDKRMVIS SLVLNWLIGP ALMFALAWLL LPDLPEYRTG LIIVGLARCI
AMVIIWNDLA RGDREAAAVL VALNSVFQVV MFGVLGWFYL QVLPGWLGLD TAALDVNVWS
IAKSVLVFLG IPLLAGYLSR RLGEKAKGRQ WYESKYLPKV GPVALYGLLF TIVVLFALQG
HTITAKPWDV ARIALPLLAY FTIMWAGSYA LGKAIGLRYA RTTTLAFTAA GNNFELAIAV
AIGVFGVTSG QALAGVVGPL IEVPVLVALV YVSLWLRKRW SHSDAHITDP RPAGHVVDRH
PPKQTRTPPQ ATHQCVPLVR TA
//
