ID A0A561VLS3_ACTTI Unreviewed; 913 AA.
AC A0A561VLS3;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Calcium-translocating P-type ATPase {ECO:0000313|EMBL:TWG12563.1};
GN ORFNames=FHX34_105430 {ECO:0000313|EMBL:TWG12563.1};
OS Actinoplanes teichomyceticus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1867 {ECO:0000313|EMBL:TWG12563.1, ECO:0000313|Proteomes:UP000320239};
RN [1] {ECO:0000313|EMBL:TWG12563.1, ECO:0000313|Proteomes:UP000320239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43866 {ECO:0000313|EMBL:TWG12563.1,
RC ECO:0000313|Proteomes:UP000320239};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWG12563.1}.
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DR EMBL; VIWY01000005; TWG12563.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A561VLS3; -.
DR OrthoDB; 9814270at2; -.
DR Proteomes; UP000320239; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43294:SF22; P-TYPE ATPASE; 1.
DR PANTHER; PTHR43294; SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000320239};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 678..699
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 705..727
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 753..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 798..816
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 828..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 856..880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..84
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
FT REGION 894..913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 913 AA; 96079 MW; 0B24F66B299FC15D CRC64;
MAQTMTAPAE VDERQPPTEL FRHLRSSPAG LRSREAAHRL TVFGPNELSR RHGRRWPRQL
RAQLTQPLAV LLMVAAMLAW AGHSAPLAVA VLAVIALNAG FAFVQERQAE QAVEALAAYL
PASARVMRDG APVEVPAREL VPGDVMEVAE GDRICADARL IDGVVAVDMS ALNGESVPVT
RAADAEPVPG PLLEARELIF SGTSCTAGQA RAVVTHTAMH TEIGRIAALS QRGRVEPSPL
ERQVRRATWI IAVAAVAAGL GFLPIGVLAG LGWTAAVTFA IGLIVANVPE GLLPTITLAL
AAGIRELARA GAVVKRLSAV ETLGSTTVIC TDKTGTLTEN RMRVTRVWLA GADRDVAAAG
PDRNLRDLAL AAAVCTTARP ADGGDPADGG DPTELALLRL AETAGVAVDP AGRDAARTAL
YAFDPRDKRM SVVTAGRLYT KGAPESVLPL CTTALDAQGR AAALTDRHRA GVMAAVDRYA
CAGLRVIAVA RRVAAPQRLT AGRRAAETGL TFLGLVAMVD PPRPAVPEAV AAAHRAGITV
HVITGDYGPT AAEVAAKVGI GHGRLRIVTG AALDRMGDAA LDRLLADRRE TVFARSSPEG
KLRICEALRA EGHIVAMTGD GVNDAPALRH ADIGVAMGRS GTDVAREAAT MVLTDDNFAT
IVRAVEAGRR VYDNVRKFVL YIFAHAVPEI VPFLVFALSG GAVPVPLTVL QILAIDLGTE
TLPALALSRE RAEPGLMDRP PRAPRTGIID RRLLWRAWGL LGVTSAVLVM AGFCWTLWRI
GWRPGDALPP AAHARATTMT FAGIVACQIG TAFASRTDHA SLRSIGVFSN RLLLGGIAFE
LAFAAALIWL PPLRPLFGTA PLGGAELAFL APFPVIVWGV DEIYRARLRR RGPRPAMAGP
ATWTTHPVPA PGS
//
