ID A0A562IH65_MICOL Unreviewed; 310 AA.
AC A0A562IH65;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 28-JUN-2023, entry version 12.
DE SubName: Full=Regulator of protease activity HflC (Stomatin/prohibitin superfamily) {ECO:0000313|EMBL:TWH70357.1};
GN ORFNames=JD77_05382 {ECO:0000313|EMBL:TWH70357.1};
OS Micromonospora olivasterospora.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1880 {ECO:0000313|EMBL:TWH70357.1, ECO:0000313|Proteomes:UP000319825};
RN [1] {ECO:0000313|EMBL:TWH70357.1, ECO:0000313|Proteomes:UP000319825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43868 {ECO:0000313|EMBL:TWH70357.1,
RC ECO:0000313|Proteomes:UP000319825};
RA Klenk H.-P.;
RT "R&d 2014.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the band 7/mec-2 family.
CC {ECO:0000256|ARBA:ARBA00008164}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWH70357.1}.
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DR EMBL; VLKE01000001; TWH70357.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A562IH65; -.
DR Proteomes; UP000319825; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 6.10.250.2090; -; 1.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR InterPro; IPR043202; Band-7_stomatin-like.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR001972; Stomatin_HflK_fam.
DR PANTHER; PTHR10264:SF19; AT06885P-RELATED; 1.
DR PANTHER; PTHR10264; BAND 7 PROTEIN-RELATED; 1.
DR Pfam; PF01145; Band_7; 1.
DR PRINTS; PR00721; STOMATIN.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:TWH70357.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:TWH70357.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000319825};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..195
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
FT REGION 272..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 310 AA; 33771 MW; 8FD4E8F75E429B5B CRC64;
MRRREAEASG IEGDMAVGAV VGLIIVVVLA LLLLALSVRM VQQYQRGIVF RFGRVLDRVR
QPGLQLIVPV ADRMVRVSMQ TTVIGVPAQG VITRDNVTLT VDAVVYYRVV DPVKALVNVR
DYPAAVLQVA QTALRSVIGK ADLDTLLRDR DRINAELKAV IDAPTEKPWG LLIERVEVKD
VSLPEGMKRS MSRQAEAERE RRARVIAADG EFQASRRLAD ASRTMADTPG AYQLRLLQTV
VDVAAEKNST LVMPFPVELL RFFDVVARGH RPAEPAAAPG GGPSGTPERE PVAAPTGERA
DGHRGQPPAR
//
