ID A0A5A7NLC5_9MICC Unreviewed; 383 AA.
AC A0A5A7NLC5;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=AI-2E family transporter {ECO:0000313|EMBL:GER21754.1};
GN ORFNames=NCCP1664_02510 {ECO:0000313|EMBL:GER21754.1};
OS Zafaria cholistanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Zafaria.
OX NCBI_TaxID=1682741 {ECO:0000313|EMBL:GER21754.1, ECO:0000313|Proteomes:UP000325307};
RN [1] {ECO:0000313|EMBL:GER21754.1, ECO:0000313|Proteomes:UP000325307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCCP-1664 {ECO:0000313|EMBL:GER21754.1,
RC ECO:0000313|Proteomes:UP000325307};
RA Amin A., Ahmed I., Khalid N., Schumann P., Busse H.J., Khan I.U., Li S.,
RA Li W.J.;
RT "Arthrobacter zafarii sp. nov., a moderately thermotolerant and
RT halotolerant actinobacterium isolated from Cholistan desert soil of
RT Pakistan.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GER21754.1}.
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DR EMBL; BKDJ01000001; GER21754.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5A7NLC5; -.
DR OrthoDB; 9784366at2; -.
DR Proteomes; UP000325307; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF75; TRANSPORT PROTEIN SLL0063-RELATED; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
DR PRINTS; PR00173; EDTRNSPORT.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000325307};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 28..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 360..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 383 AA; 39224 MW; CCDBECC645827058 CRC64;
MARSPHWASP KPGAGPWADP LGRSATRAAQ LLLVLTAVSV AVYGLIQLKL VVIPLMIALI
LSAALSPVVA ALRRRGLRPG LATWTTFLAA VLVLGGIITA LVFAVRSEWD ELVASAIAGW
EELRALLEDG PLQVDQAAID QAVAALVGFA GSRQFGLGAL SGISAAAEVV TGGLLCAVVL
FYFLKDGDRI WSFFLRGFEG TRRDRMHRAG QRALEVLGKY VHGTAVVAFV DALAIGVALL
LLRVPLALPL AVLVFLGGFV PMVGATLTGI FAALVALVAN GPVVALIVVA VVVAVNQLDG
DVLQPLVMGR TLRLHGLVIL LALAAGVVLA GIAGAVLAVP VTAVAWAVLK VWREPPAQAG
TGLAAGDAGE VEGAPDAAPG PAS
//
