ID A0A5A7SBS2_9NOCA Unreviewed; 852 AA.
AC A0A5A7SBS2;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit {ECO:0000313|EMBL:KAA0022043.1};
GN ORFNames=FOY51_16850 {ECO:0000313|EMBL:KAA0022043.1};
OS Spelaeibacter cavernicola.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Spelaeibacter.
OX NCBI_TaxID=2495913 {ECO:0000313|EMBL:KAA0022043.1, ECO:0000313|Proteomes:UP000322244};
RN [1] {ECO:0000313|EMBL:KAA0022043.1, ECO:0000313|Proteomes:UP000322244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C1-24 {ECO:0000313|EMBL:KAA0022043.1,
RC ECO:0000313|Proteomes:UP000322244};
RA Lee S.D.;
RT "Rhodococcus cavernicolus sp. nov., isolated from a cave.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA0022043.1}.
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DR EMBL; VLNY01000007; KAA0022043.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5A7SBS2; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000322244; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS50151; UVR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:KAA0022043.1};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Hydrolase {ECO:0000313|EMBL:KAA0022043.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000313|EMBL:KAA0022043.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000322244};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 2..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 424..459
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 145..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 813..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..828
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 852 AA; 94304 MW; 4177DDC00FAB3B41 CRC64;
MFERFTDRAR RVVVLAQEEA RMLNHNYIGT EHILLGLIHE GEGVAAKSLE SLGISLEGVR
SQVEEIIGQG QQAPSGHIPF TPRAKKVLEL SLREALQLGH NYIGTEHILL GLIREGEGVA
AQVLVKLGAD LNRVRQQVIQ LLSGYQGKEP SESGSGRGGE AGTPSTSLVL DQFGRNLTQA
ALEGKLDPVI GRAKEIERVM QVLSRRTKNN PVLIGEPGVG KTAVVEGLAQ AIVNGEVPET
LKDKQLYTLD LGSLVAGSRY RGDFEERLKK VLKEINTRGD IILFIDELHT LVGAGAAEGA
IDAASILKPK LARGELQTIG ATTLDEYRKY IEKDAALERR FQPVQVGEPT VEHTIDILKG
LRDRYEAHHR VSITDSALVA AATLADRYIN DRFLPDKAID LIDEAGARMR IRRMTAPPDL
REFDDKIADA RREKESAIDA QDFEKAANLR DKEKTLVAQR AEREKQWRSG DLDVIAEVDD
EQIAEVLANW TGIPVFKLTE EETTRLLRME DELHKRIIGQ EEAVKAVAKA IRRTRAGLKD
PKRPSGSFIF AGPSGVGKTE LSKALANFLF GDDDALIQID MGEFHDRFTA SRLFGAPPGY
VGYEEGGQLT EKVRRKPFSV VLFDEIEKAH QEIYNTLLQV LEDGRLTDGQ GRTVDFKNTV
LIFTSNLGTS DISKAVGLGF AQSNVEGSNY ERMKMKVNDE LKKHFRPEFL NRIDDIVVFH
QLTTDQIVQM VDLMIARVGR QLAAKDMVME LTDKAKSLLA KRGFDPVLGA RPLRRTIQRE
IEDQLSEKIL FNELTPGQIV FVDVDNWDGE GQGEDAKFTF RGEQKPVHVP DSPEGVLAGA
SESGSSSESI GE
//
