ID A0A5A7UUL9_CUCME Unreviewed; 349 AA.
AC A0A5A7UUL9;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Xylem cysteine proteinase 1-like {ECO:0000313|EMBL:KAA0059602.1};
GN ORFNames=E5676_scaffold886G00130 {ECO:0000313|EMBL:TYK08135.1},
GN E6C27_scaffold54G00240 {ECO:0000313|EMBL:KAA0059602.1};
OS Cucumis melo var. makuwa.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=1194695 {ECO:0000313|EMBL:KAA0059602.1, ECO:0000313|Proteomes:UP000321393};
RN [1] {ECO:0000313|Proteomes:UP000321393, ECO:0000313|Proteomes:UP000321947}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chang Bougi {ECO:0000313|Proteomes:UP000321947}, and cv. SW
RC 3 {ECO:0000313|Proteomes:UP000321393};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAA0059602.1};
RA Kwon S.-Y.;
RT "Draft genome sequences of two oriental melons (Cucumis melo L. var
RT makuwa).";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA0059602.1}.
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DR EMBL; SSTE01006004; KAA0059602.1; -; Genomic_DNA.
DR EMBL; SSTD01012919; TYK08135.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5A7UUL9; -.
DR Proteomes; UP000321393; Unassembled WGS sequence.
DR Proteomes; UP000321947; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF357; OS01G0971400 PROTEIN; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000321393};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT DOMAIN 47..103
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 131..346
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 349 AA; 39410 MW; 6DE46B15E7C6D505 CRC64;
MAFSTFSKTT LILSATLFIT YGIAHDFSIV GYSPEHLASM DKTIELFESW MSKHSKTYRS
VEEKLHRFEI FLDNLKHIDE TNKKVSSYWL GLNEFADLSH EEFKSKYLGL RVEFPRKRSS
RGFSYRDVED LPESVDWRTK GAVTPVKNQG SCGSCWAFST VAAVEGINQI VTGNLTSLSE
QELIDCDRSF NNGCYGGLMD YAFQYIMSNS GLRKEEDYPY LMEEGRCIRE KEQFEVVTIS
GYEDVPANDE QSLLKALSHQ PVSVAIEASG RNFQFYKGGI FTGRCGTEMD HGVTAVGYGS
SEGTDYIIVK NSWGPKWGEN GYIRMKRNTG KPEGLCGINQ MASYPTKEK
//
