ID   A0A5A9MVX5_9TELE        Unreviewed;       206 AA.
AC   A0A5A9MVX5;
DT   13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Claudin-4 {ECO:0000313|EMBL:KAA0701690.1};
GN   ORFNames=E1301_Tti018539 {ECO:0000313|EMBL:KAA0701690.1};
OS   Triplophysa tibetana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Nemacheilidae; Triplophysa.
OX   NCBI_TaxID=1572043 {ECO:0000313|EMBL:KAA0701690.1, ECO:0000313|Proteomes:UP000324632};
RN   [1] {ECO:0000313|EMBL:KAA0701690.1, ECO:0000313|Proteomes:UP000324632}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TTIB1903HZAU {ECO:0000313|EMBL:KAA0701690.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:KAA0701690.1};
RX   PubMed=30977968;
RA   Yang X., Liu H., Ma Z., Zou Y., Zou M., Mao Y., Li X., Wang H., Chen T.,
RA   Wang W., Yang R.;
RT   "Chromosome-level genome assembly of Triplophysa tibetana, a fish adapted
RT   to the harsh high-altitude environment of the Tibetan Plateau.";
RL   Mol. Ecol. Resour. 19:1027-1036(2019).
CC   -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC       {ECO:0000256|ARBA:ARBA00004435}.
CC   -!- SIMILARITY: Belongs to the claudin family.
CC       {ECO:0000256|ARBA:ARBA00008295}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAA0701690.1}.
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DR   EMBL; SOYY01000025; KAA0701690.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5A9MVX5; -.
DR   Proteomes; UP000324632; Chromosome 25.
DR   GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR006187; Claudin.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   PANTHER; PTHR12002; CLAUDIN; 1.
DR   PANTHER; PTHR12002:SF216; CLAUDIN B-RELATED; 1.
DR   Pfam; PF00822; PMP22_Claudin; 1.
DR   PRINTS; PR01077; CLAUDIN.
PE   3: Inferred from homology;
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000324632};
KW   Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        119..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        160..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   206 AA;  21500 MW;  F1DE2A3B7624BA02 CRC64;
     MASAGLQMLG IALGIIGWIG VILACALPMW LVTAFIGQNI VTAQTTWEGI WMTCVVQSTG
     QMQCKVYDSM LALSSDMQAA RAMCIVSILL GLVGILLAGA GGKCTNCIED ENVKSKVGIV
     AGVVFIIGGV LCLVPVCWTA NTAIRDFYNP LTPGSMKKEL GASLFIGWGA SALLIIAGAM
     LCANCPPKDQ YGVKYTARPG GTKGYV
//