ID A0A5A9N6U4_9TELE Unreviewed; 440 AA.
AC A0A5A9N6U4;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE RecName: Full=Glial fibrillary acidic protein {ECO:0000256|ARBA:ARBA00018571};
GN ORFNames=E1301_Tti004466 {ECO:0000313|EMBL:KAA0705704.1};
OS Triplophysa tibetana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Nemacheilidae; Triplophysa.
OX NCBI_TaxID=1572043 {ECO:0000313|EMBL:KAA0705704.1, ECO:0000313|Proteomes:UP000324632};
RN [1] {ECO:0000313|EMBL:KAA0705704.1, ECO:0000313|Proteomes:UP000324632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTIB1903HZAU {ECO:0000313|EMBL:KAA0705704.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAA0705704.1};
RX PubMed=30977968;
RA Yang X., Liu H., Ma Z., Zou Y., Zou M., Mao Y., Li X., Wang H., Chen T.,
RA Wang W., Yang R.;
RT "Chromosome-level genome assembly of Triplophysa tibetana, a fish adapted
RT to the harsh high-altitude environment of the Tibetan Plateau.";
RL Mol. Ecol. Resour. 19:1027-1036(2019).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA0705704.1}.
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DR EMBL; SOYY01000021; KAA0705704.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5A9N6U4; -.
DR Proteomes; UP000324632; Chromosome 21.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF9; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000324632}.
FT DOMAIN 81..389
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 99..233
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 276..367
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 20..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 50825 MW; 433B69E6CC3579FE CRC64;
METQRVYSSY RKRFGTPGGS SPAGITSRLS SSRLSLHSSP RHLTSSPMTH STSRLSLGGD
RLDFSADSLL KAQYRENRTN EKVEMMGLND RFASYIEKVR FLEQQNKMLV AELNQLRGKE
PSRLGDIYQE ELRELRRQVD GLNTGKARLE IERDNLASDL GSVKQRLQDE TVLRQEAENN
LNTFRQDVDE AAMNRVQLER KIDALQDEIN FLKKVHEEEM RELQEQLMAQ QVHVDLDVSK
PDLTAALKDI RAQYEAMATS NMQETEEWYR SKFSDLTDAA NRNAEALRQA KQEANEYRRQ
VQSLTCDLES LRGTNESLER QLREMDERFT LETAGYQDTI ARLEDEIQML KEEMARHLQE
YQDLLNVKLA LDIEIATYRK LLEGEETRLL KSPLLSERIC RNDSQALDRL PSLTKASGCC
DQGNFFNVLS TFPAYPFLEF
//
