ID A0A5A9NG61_9TELE Unreviewed; 585 AA.
AC A0A5A9NG61;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=T-box brain protein 1 {ECO:0000313|EMBL:KAA0707821.1};
GN ORFNames=E1301_Tti009701 {ECO:0000313|EMBL:KAA0707821.1};
OS Triplophysa tibetana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Nemacheilidae; Triplophysa.
OX NCBI_TaxID=1572043 {ECO:0000313|EMBL:KAA0707821.1, ECO:0000313|Proteomes:UP000324632};
RN [1] {ECO:0000313|EMBL:KAA0707821.1, ECO:0000313|Proteomes:UP000324632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTIB1903HZAU {ECO:0000313|EMBL:KAA0707821.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAA0707821.1};
RX PubMed=30977968;
RA Yang X., Liu H., Ma Z., Zou Y., Zou M., Mao Y., Li X., Wang H., Chen T.,
RA Wang W., Yang R.;
RT "Chromosome-level genome assembly of Triplophysa tibetana, a fish adapted
RT to the harsh high-altitude environment of the Tibetan Plateau.";
RL Mol. Ecol. Resour. 19:1027-1036(2019).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA0707821.1}.
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DR EMBL; SOYY01000019; KAA0707821.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5A9NG61; -.
DR Proteomes; UP000324632; Chromosome 19.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0009790; P:embryo development; IEA:UniProt.
DR GO; GO:0060429; P:epithelium development; IEA:UniProt.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20194; T-box_TBR1_2_21-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032385; T-box_assoc.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267:SF88; T-BOX BRAIN PROTEIN 1; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR Pfam; PF16176; T-box_assoc; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000324632};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 170..353
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 1..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..83
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 585 AA; 64771 MW; 221614E9ADD135E3 CRC64;
MHLHQLPSSS RLTEKRTSVD DDFTCNIGPG EDRVSSSGDS LESEPPLKRF STGIRNTSHD
LTDVRDEDGG ARDTARNDGE SIDKCFLPDS TQARGDYVSS SDMFLYSGQQ HVAPALPAFS
GHYVTPHPVI ASGQYNGLSY AYSHAYGQTY ANNSAVYPFP SVPGKAQVHL CNRALWFKFH
RHQTEMIVTK QGRRMFPFLS LSMSGLDPAR HYNIVVDVIL ADPNHWRFQG GKWVPCGKAD
TNVTANRVFM HTDSPNTGAH WMRQEISFSK LKLTNNKGAI SNSTQMIVLQ SLHKYQPRIH
VMEIDENGEE KSPDRAQTFT FPETQFMAVT AYQNTDVTQL KIDHNPFAKG FRDNYETSYI
GCETDQLTPT SDAPRSHTLS ASRYAMTNAL FQDQFLNSYT KSCFTTLASN TSSSDRVITL
TNSPITQTQT QDSMTSGQRW FVSSSAAPSY EADINTAALF SYATVGVKSL PNTGGLDCYT
SPSGWDLLDS AEISNKTSNL TGWDATLERS TQPNYLQVDG DILEMDRSTL EGNDAGDLTW
TETQSSIKSV DSSDFRILEE VKHTSPSITP VSEIQTENRI AGVTG
//
