ID A0A5A9PIW9_9TELE Unreviewed; 423 AA.
AC A0A5A9PIW9;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Transcription factor GATA-3 GATA-binding factor 3 {ECO:0000313|EMBL:KAA0721131.1};
GN ORFNames=E1301_Tti001859 {ECO:0000313|EMBL:KAA0721131.1};
OS Triplophysa tibetana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Nemacheilidae; Triplophysa.
OX NCBI_TaxID=1572043 {ECO:0000313|EMBL:KAA0721131.1, ECO:0000313|Proteomes:UP000324632};
RN [1] {ECO:0000313|EMBL:KAA0721131.1, ECO:0000313|Proteomes:UP000324632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTIB1903HZAU {ECO:0000313|EMBL:KAA0721131.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAA0721131.1};
RX PubMed=30977968;
RA Yang X., Liu H., Ma Z., Zou Y., Zou M., Mao Y., Li X., Wang H., Chen T.,
RA Wang W., Yang R.;
RT "Chromosome-level genome assembly of Triplophysa tibetana, a fish adapted
RT to the harsh high-altitude environment of the Tibetan Plateau.";
RL Mol. Ecol. Resour. 19:1027-1036(2019).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA0721131.1}.
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DR EMBL; SOYY01000005; KAA0721131.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5A9PIW9; -.
DR Proteomes; UP000324632; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00202; ZnF_GATA; 2.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 2.
DR InterPro; IPR016374; TF_GATA-2/3.
DR InterPro; IPR039355; Transcription_factor_GATA.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR10071:SF106; TRANS-ACTING T-CELL-SPECIFIC TRANSCRIPTION FACTOR GATA-3; 1.
DR PANTHER; PTHR10071; TRANSCRIPTION FACTOR GATA FAMILY MEMBER; 1.
DR Pfam; PF00320; GATA; 2.
DR PIRSF; PIRSF003027; TF_GATA-1/2/3; 1.
DR PRINTS; PR00619; GATAZNFINGER.
DR SMART; SM00401; ZnF_GATA; 2.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 2.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 2.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000324632};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00094}.
FT DOMAIN 235..289
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT DOMAIN 289..342
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT REGION 103..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 45983 MW; 8FD59512AE859B49 CRC64;
MEVSPEQPRW VTHHHPVING QHPETHHPGL GHSYMDPSQY SLPEDVDVLF NIDGQSNHPY
YGNSVRAVQR YPPPHHSSQV CRPSLLHGSL PWLDGSKGIG PHHSTSPWNL GPFPKTSLHH
SSPGSLSVYP PASSSSLSGG HSSPHLFTFP PTPPKDVSPD PTISTSGSGS TLRQEDKECI
KYQVSLAESM KLDSAHSRGM ASIGAGASSA HHHPIAAYPS YVSDYGPGLF PPSSLIEGRE
CVNCGATSTP LWRRDGTGHY LCNACGLYHK MNGQNRPLIK PKRRLSAARR AGTSCANCQT
TTTTLWRRNA NGDPVCNACG LYYKLHNINR PLTMKKEGIQ TRNRKMSSKS KKSKKSHDSM
DDFSKSLMDK SSSFSPAALS RHMSSFPPFS HSGHMLTTPT PMHPSSGLSF GPHHPSSMVT
AMG
//
