ID   A0A5B1LJB0_9ACTN        Unreviewed;       453 AA.
AC   A0A5B1LJB0;
DT   13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=AI-2E family transporter {ECO:0000313|EMBL:KAA1419669.1};
GN   ORFNames=F0U44_10900 {ECO:0000313|EMBL:KAA1419669.1};
OS   Nocardioides humilatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=2607660 {ECO:0000313|EMBL:KAA1419669.1, ECO:0000313|Proteomes:UP000325003};
RN   [1] {ECO:0000313|EMBL:KAA1419669.1, ECO:0000313|Proteomes:UP000325003}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BN130099 {ECO:0000313|EMBL:KAA1419669.1,
RC   ECO:0000313|Proteomes:UP000325003};
RA   Cho C.;
RT   "Nocardioides panacisoli sp. nov., isolated from the soil of a ginseng
RT   field.";
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KAA1419669.1, ECO:0000313|Proteomes:UP000325003}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BN130099 {ECO:0000313|EMBL:KAA1419669.1,
RC   ECO:0000313|Proteomes:UP000325003};
RA   Jin C.;
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC       family. {ECO:0000256|ARBA:ARBA00009773}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAA1419669.1}.
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DR   EMBL; VUJV01000003; KAA1419669.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5B1LJB0; -.
DR   Proteomes; UP000325003; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002549; AI-2E-like.
DR   PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR   PANTHER; PTHR21716:SF75; TRANSPORT PROTEIN SLL0063-RELATED; 1.
DR   Pfam; PF01594; AI-2E_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000325003};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        88..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        150..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        293..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        392..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..28
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   453 AA;  48215 MW;  32747E72181203FE CRC64;
     MRDDEAPKEL GEELAGDHEE GHEEDHRHRP RFTRRRRVDE GEDPDEDAVA TVLQRFAHQW
     ALAREERRGG PAPLLTGPSR TGRAEVPWGL DLAAAWAWRL LIIAAAGYLV MWLAGYFAVV
     TIPIAVALLF SALSWPMVHL LIRLKIPKGL AAGLVVLGGI TAVAALLTFA GQQVATGAED
     LADQTVKGLE EIRTWLRDGP VNASDSQIND WIKSAQDMIT ERSKDGEVLG RVTEVGSALG
     HVVAGFFITL FATYFFLADG DRIWAWIVRL APRGARERVD SSGKVAWLSL VQFVRATVIV
     AAVDAIGIMI GAAILKVPFV LAIGVLVFLG AFVPVIGATI AGSVAVLVAL VDQGPVTALI
     MAGVLIGVQQ LEGHVLQPFL LGRWVQLHPL GVILAIAGGV LVAGVVGALV AVPLAAAANA
     VVLHLAELSQ MSLAEAEEAL DDDIIHPEGA THD
//