ID A0A5B6U2I9_9ROSI Unreviewed; 1597 AA.
AC A0A5B6U2I9;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Reverse transcriptase (RNA-dependent DNA polymerase) domain containing protein {ECO:0000313|EMBL:KAA3450814.1};
GN ORFNames=EPI10_034343 {ECO:0000313|EMBL:KAA3450814.1};
OS Gossypium australe.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=47621 {ECO:0000313|EMBL:KAA3450814.1, ECO:0000313|Proteomes:UP000325315};
RN [1] {ECO:0000313|Proteomes:UP000325315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. PA1801 {ECO:0000313|Proteomes:UP000325315};
RX PubMed=31479566; DOI=10.1111/pbi.13249;
RA Cai Y., Cai X., Wang Q., Wang P., Zhang Y., Cai C., Xu Y., Wang K.,
RA Zhou Z., Wang C., Geng S., Li B., Dong Q., Hou Y., Wang H., Ai P., Liu Z.,
RA Yi F., Sun M., An G., Cheng J., Zhang Y., Shi Q., Xie Y., Shi X., Chang Y.,
RA Huang F., Chen Y., Hong S., Mi L., Sun Q., Zhang L., Zhou B., Peng R.,
RA Zhang X., Liu F.;
RT "Genome sequencing of the Australian wild diploid species Gossypium
RT australe highlights disease resistance and delayed gland morphogenesis.";
RL Plant Biotechnol. J. 0:0-0(2019).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA3450814.1}.
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DR EMBL; SMMG02000121; KAA3450814.1; -; Genomic_DNA.
DR Proteomes; UP000325315; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09279; RNase_HI_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.10.20.370; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000313|EMBL:KAA3450814.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000325315};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:KAA3450814.1};
KW Transferase {ECO:0000313|EMBL:KAA3450814.1}.
FT DOMAIN 1049..1209
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 48..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1597 AA; 182824 MW; 3828A1E3DB91F25D CRC64;
MAQLTPLDKL QLNKCTKENL FSQTVGMELA SLLSPELLHV FSSISGKDSK KKNAIRGENT
KKTNTEKKRR ACSRARTHCW NEGLKLPTRN NCPGCNDRYV EYRQDIAKRR SVHERIGRIH
PSDNRRLELH NDQPKKRHAD HRWIDREEEE DHGYIWQEGQ WCPPGLRKSQ KRRVQRLRNQ
ELKQARPRMK SVWRRVEKPD EHNPPAPTCM VCLLPSEFMA PTDQVVQEEA LSEVDETEQL
MAQLMLSKQA TFEKPSKNRH MKPLYLRGFV NGKPLTKMFV DGGAAVNVMP YTTFRKLGMG
LGDLTPTSIV LNDFAGNPSD TKGCVHVDLM IGSKTLLTTF FVIEGRGSYS LLLGRDWIHA
NCCIPSTMHQ QLIQWIDDEV EIVQADDSIS VARRGFVSAD KLEEVDIGDG DKPRPTFISA
NLDPIFKEKL IKLLKEYKDC FAWDYSEMPG LDRSIVEHRL PIKPGYKPYK QPPRKIYKEE
VLADVKKEIE RLLDANFIRP CKYADWISNI VPVYKKNGKM RVCIDFRDLN KANQWMDTQC
LFMDGNAGYN QIFMALEDIV KTAFRCPGHI GLFEWVVMTF GLKNAGATYQ RAMNYIFHEL
IGKIVEYILM IIGWRIPGIL IHEGGIGVGK KSMKAIDEII PPTNLKELQS LLGKINFVRR
FISNLSQKVL PFSSLLKVKK DQKFIWGDEQ QKAFDEIKEY MKEPPVLVPP QLNKPFKLYM
AADAQTIGSA LIQEFEGKER VVAYLSRKLL DPETRYSAME KLSLCHMLSM PILNGRIGKW
ILALSEFELK FESAKAVKGQ IIADFITEHR DSSINLLNII PWVLFFDGSS CDKGGGAGIL
LTSPKGEVFK FAIPNQSTVT NNQAEYEALL KGLQYLKEAR AIALSGEYEC KNDVLRNYYE
ECKQILKGFR SIILQHIPRG DNEEANKLAQ SASGYRENQE VFTTDDCAIR SDLAENDWRK
EIADYLENPS QKVSRRLRYK AIKFVLLDKD LYYKSLDGVL LRCLNQEEAK KLMSEVHDGL
CGAHQSAYRM KWKFGNIQRV PASALNPIIK PWPFRGWGID LIGQIYPPSS KGHKFVLLAT
DYFTKWVEAI PLRNVASENM IEFVKEHIIY RFGIPQTITT DQGTQFTSSE FRDFAESMGI
KLLNSSPYYA QANGQAEASN KIMIKIIQKK IDQKPRKWHS VLNEALWAYR MAPHGSTKTS
PYELVCGHHA VLPWEVQSDS RRIKLQKDLS SKDYNDLMMD ELEDLHMIRL KALENIEKNK
MRIAKYYNKK VKVKQFTEGD LVWKALLPIG TKYSAFGKWS PNWEGPFRIF KCIIYKKEGT
RLQWGLIDPP KPMPNREIMV KRISQIRPRF LHVLHGMFYS TLQASFTYIK STVVGAGMNL
HGIKGECCTI AHTGPGDIRK DLVDVVHPIQ GRPACCIGRM GKLDNCGFQS VKPRKKIRNK
KILTSSSPPS NVAFPGDLIN LLILILQDVL EVDNLMNQCR MRRIQNCACF PQKTSLDDDE
RKKKCSLESG IGTRQSWNVS RNEVRRQFKK TIKRAFGKIL KMTSGPSKKL KGHSPRSVTC
FMTVRAPEKR TELLSSALVE VINNIAQEYA SPRCVCV
//
