ID   A0A5B8MXY9_9CHLO        Unreviewed;       503 AA.
AC   A0A5B8MXY9;
DT   13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=rRNA methyltransferase {ECO:0000313|EMBL:QDZ24370.1};
GN   ORFNames=A3770_13p68880 {ECO:0000313|EMBL:QDZ24370.1};
OS   Chloropicon primus.
OC   Eukaryota; Viridiplantae; Chlorophyta; Chloropicophyceae; Chloropicales;
OC   Chloropicaceae; Chloropicon.
OX   NCBI_TaxID=1764295 {ECO:0000313|EMBL:QDZ24370.1, ECO:0000313|Proteomes:UP000316726};
RN   [1] {ECO:0000313|EMBL:QDZ24370.1, ECO:0000313|Proteomes:UP000316726}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1205 {ECO:0000313|EMBL:QDZ24370.1,
RC   ECO:0000313|Proteomes:UP000316726};
RA   Pombert J.-F., Otis C., Turmel M., Lemieux C.;
RT   "The complete nuclear genome of the prasinophyte Chloropicon primus
RT   (CCMP1205).";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
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DR   EMBL; CP031046; QDZ24370.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5B8MXY9; -.
DR   STRING; 1764295.A0A5B8MXY9; -.
DR   Proteomes; UP000316726; Chromosome 13.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR   InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR   InterPro; IPR023267; RCMT.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR22807:SF4; 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR   Pfam; PF01189; Methyltr_RsmB-F; 1.
DR   PRINTS; PR02008; RCMTFAMILY.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000316726};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU01023};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01023};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}.
FT   DOMAIN          183..496
FT                   /note="SAM-dependent MTase RsmB/NOP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51686"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          101..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        429
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         277..283
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         316
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         344
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         365
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ   SEQUENCE   503 AA;  55587 MW;  725C71336BDA1B14 CRC64;
     MKRPRRSPPG GETRGRARHG DQKQLGGSFQ SAHHQAADIV AQLLRAKSQR RGGASIKSLV
     YANEIQNKKK VYALCCETLK HLTIIKEVLR EAKFVLPEGK FRTKGDGGEE DKPASFADSG
     AGTTRKAGLV YVWVYELLFG QWDKIQKSRK FNPVVKQETE LVEAYDLVKT RPSSSNSDGG
     KLLSPLESKT FPKYLRVNTL KISVDEAFQS LSAEYGADNV KRNKYLGDVL ELPASVTDLY
     SQRLVRNGSV VQQGLSSCMP VHALEPLQKS WCLIDACSAP GNKTTQLAAH LAMASGGSNA
     TGGRDQAAVG KIFAFDLDPN RFERLKKNVR HCGAGSIVLP ELRDFLAVDH RKEKKFAAVK
     AILLDPSCSG SGTIHSRGDY LLGLKASDSS PQQSESDKRR VDTLASFQEK CLRHALNFPN
     VERVVYSTCS IHVRENETVV ASVLAEAERL GFQLEKALPQ WPRRGYPLFE TCDKLVRVNP
     NKDKSDGFFL ALFVRKQKTA GPR
//