ID A0A5C0SB49_9CLOT Unreviewed; 817 AA.
AC A0A5C0SB49;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit {ECO:0000313|EMBL:QEK11132.1};
GN ORFNames=FQB35_01445 {ECO:0000313|EMBL:QEK11132.1};
OS Crassaminicella thermophila.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Crassaminicella.
OX NCBI_TaxID=2599308 {ECO:0000313|EMBL:QEK11132.1, ECO:0000313|Proteomes:UP000324646};
RN [1] {ECO:0000313|EMBL:QEK11132.1, ECO:0000313|Proteomes:UP000324646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY095 {ECO:0000313|EMBL:QEK11132.1,
RC ECO:0000313|Proteomes:UP000324646};
RA Li X.;
RT "Complete genome of Crassaminicella thermophila SY095.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
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DR EMBL; CP042243; QEK11132.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C0SB49; -.
DR KEGG; crs:FQB35_01445; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000324646; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:QEK11132.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:QEK11132.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000324646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 4..146
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 421..456
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 417..467
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 726..753
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 817 AA; 91495 MW; 293E128F63707B0F CRC64;
MDMFARFTER AQKVVIFAQE EAKSLRHNYV GTEHLLLGLV KEGGGIAAKA LTNMGVSLDK
IKQKIVSMIG VGSELNPQLL GFTPRTKRIF ELSFAEARRL GHNYIGTEHL LLGLIREGEG
VAAKILIDSG VNLTKAREEV MKLLGSTMSP NGGEGVSSVN NKNTPTLNKY GRDLTEMARE
GKLDPVIGRS KEIERVIQIL SRRTKNNPCL IGEPGVGKTA IAEGLAQKIV EGNIPEILKD
KRVVTLDLAS MVAGAKYRGE FEDRLKKVMD ELRQSKDVIL FIDEMHTIIG AGGAEGAIDA
SNILKPALAR GEIQAIGATT LDEYRKHIEK DAALERRFQP IHVEEPTVEE TIQILKGLRD
KYEAHHGVKI TDKAIEAAAN LSHRYITDRF LPDKAVDLID EAASKIRLKI VTQPPELKDL
EEKLEELAKE KEEAISAQDF ERAASVRDKE KQVKEELDNR KNNWRVNQTD KATVGEEEIA
ETVSSWTGIP VKKLAQEESE KLLHMEEILH ERVIGQEESV KAIARAVRRA RVGLKDPKRP
IGSFIFLGPT GVGKTELSKA LAEALFGDED ALIRIDMSEY MEKHAVSRLV GSPPGYVGYE
EGGQLTEKVR RKPYSVVLFD EIEKAHPDVF NILLQILDDG RLTDSKGKVV DFKNTVIIMT
SNVGAHTIKK QKTLGFAENV EDEKQSAYEK MKENVMSELR RNFRPEFLNR IDEVIVFHAL
EQEHINEIVE LMIKDLTKRM KELNIKIEIS EAAKKLLGEK GFDPEYGARP LKRAIRRMLE
DALSEEILKG NISKNDDIFV DVEDGKIVFK NKVKLNK
//
