ID A0A5C3LPS7_9AGAR Unreviewed; 962 AA.
AC A0A5C3LPS7;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401, ECO:0000256|PIRNR:PIRNR036578};
GN ORFNames=BDQ12DRAFT_656019 {ECO:0000313|EMBL:TFK35074.1};
OS Crucibulum laeve.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Nidulariaceae; Crucibulum.
OX NCBI_TaxID=68775 {ECO:0000313|EMBL:TFK35074.1, ECO:0000313|Proteomes:UP000308652};
RN [1] {ECO:0000313|EMBL:TFK35074.1, ECO:0000313|Proteomes:UP000308652}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 166.37 {ECO:0000313|EMBL:TFK35074.1,
RC ECO:0000313|Proteomes:UP000308652};
RX PubMed=30886374; DOI=.1038/s41559-019-0834-1;
RA Varga T., Krizsan K., Foldi C., Dima B., Sanchez-Garcia M.,
RA Sanchez-Ramirez S., Szollosi G.J., Szarkandi J.G., Papp V., Albert L.,
RA Andreopoulos W., Angelini C., Antonin V., Barry K.W., Bougher N.L.,
RA Buchanan P., Buyck B., Bense V., Catcheside P., Chovatia M., Cooper J.,
RA Damon W., Desjardin D., Finy P., Geml J., Haridas S., Hughes K., Justo A.,
RA Karasinski D., Kautmanova I., Kiss B., Kocsube S., Kotiranta H.,
RA LaButti K.M., Lechner B.E., Liimatainen K., Lipzen A., Lukacs Z.,
RA Mihaltcheva S., Morgado L.N., Niskanen T., Noordeloos M.E., Ohm R.A.,
RA Ortiz-Santana B., Ovrebo C., Racz N., Riley R., Savchenko A., Shiryaev A.,
RA Soop K., Spirin V., Szebenyi C., Tomsovsky M., Tulloss R.E., Uehling J.,
RA Grigoriev I.V., Vagvolgyi C., Papp T., Martin F.M., Miettinen O.,
RA Hibbett D.S., Nagy L.G.;
RT "Megaphylogeny resolves global patterns of mushroom evolution.";
RL Nat. Ecol. Evol. 3:668-678(2019).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116, ECO:0000256|PIRNR:PIRNR036578}.
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DR EMBL; ML213625; TFK35074.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C3LPS7; -.
DR STRING; 68775.A0A5C3LPS7; -.
DR Proteomes; UP000308652; Unassembled WGS sequence.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006271; P:DNA strand elongation involved in DNA replication; IEA:UniProt.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF37; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR036578};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR036578};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR036578}; Nucleus {ECO:0000256|PIRNR:PIRNR036578};
KW Reference proteome {ECO:0000313|Proteomes:UP000308652}.
FT DOMAIN 270..351
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 921..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 357..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 32..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..191
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 962 AA; 104662 MW; 535DA0B0367D3CB5 CRC64;
MPAAKPGKTV KAGGKDIRMF FGGKASGGSQ KPVAIPASSL TSQKKPAIEI SDSVNEAPGS
PKKKPSPSKP ALKPGNVIQV DSDEEPIVHR SKPVPKPTTV AEEDSDDEPI APKKSTSSRR
KISALISSDE EEDASPPKKK AALTSSKDKP KPRASTSKIK QKQKKVEDDD YDMESPLDSP
ASEDDNYEEE DEDVKPARAR NTKPPPNKIT KAAERKTPVK KAASPSKVAG PSKEPVEEEE
EPKKKFNWAA SKAAKLAGPV AHGSKEVPDG APDALVGLAF VFTGELSSFS RDEAIELAKR
FGGRVVGQPS SKTNFVVLGD NAGPSKLAAL KKHGIKTLSE DEFLNLIGTR KGLGKLDEKT
KKKMEKEEED IKKQAKEMEK TEKAHAVGGK GVDPKTQLWT ARYAPQSLKE VCGNKGQVDK
LQQWLHDWPM SLKSGFKKPG KNGMNVYRAV LITGSPGIGK TTSAHLCAKL EGFTPIELNA
SDARSKKLVE SGMNINNTSL DGYIHGSSVT NAVGVPITDR TCLIMDEVDG MSAGDRGGVG
ALNALIKKSK IPIICIANDR GAQKLKPLVA TTFNLTFQKP QVNMIRSRIL SIAFKEKMKI
PANVIDQLIT GAQSDIRQVL NMLSTWKLSN DSMDFDEGKS LVKMNEKYAI MTPFDITSKM
LGPYLFSATA RETLGDKMEY YFQDHSFMPL FIQENYLKTQ PARVRNLEGP EKVLKELELM
DKAASSISDG DLVDSLIHGP EQHWGLMPLH AVCSTIRPAA ALYGMGAHYG GPGAMSFPQW
LGQNSKQNKL SRQLGDVQIR MRLKVSGDKA EIRQSYIPAL FPHIVKPLTE SGASAIEEVI
ETMDQYYLSK EDWDTIVELG VDDHKDELVL KKVPGATKAA FTRKYNASEH PIPFHKAQDL
GKLPKKLAGG PAPDLEEAFV DDIVDDISDD DNKGKDPDDI ANDSLIQASK KKAAPAKKKA
KK
//
