ID A0A5C3MTQ0_9AGAM Unreviewed; 857 AA.
AC A0A5C3MTQ0;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=P-loop containing nucleoside triphosphate hydrolase protein {ECO:0000313|EMBL:TFK48397.1};
GN ORFNames=OE88DRAFT_1664169 {ECO:0000313|EMBL:TFK48397.1};
OS Heliocybe sulcata.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Gloeophyllales; Gloeophyllaceae; Heliocybe.
OX NCBI_TaxID=5364 {ECO:0000313|EMBL:TFK48397.1, ECO:0000313|Proteomes:UP000305948};
RN [1] {ECO:0000313|EMBL:TFK48397.1, ECO:0000313|Proteomes:UP000305948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OMC1185 {ECO:0000313|EMBL:TFK48397.1,
RC ECO:0000313|Proteomes:UP000305948};
RX PubMed=30886374; DOI=.1038/s41559-019-0834-1;
RA Varga T., Krizsan K., Foldi C., Dima B., Sanchez-Garcia M.,
RA Sanchez-Ramirez S., Szollosi G.J., Szarkandi J.G., Papp V., Albert L.,
RA Andreopoulos W., Angelini C., Antonin V., Barry K.W., Bougher N.L.,
RA Buchanan P., Buyck B., Bense V., Catcheside P., Chovatia M., Cooper J.,
RA Damon W., Desjardin D., Finy P., Geml J., Haridas S., Hughes K., Justo A.,
RA Karasinski D., Kautmanova I., Kiss B., Kocsube S., Kotiranta H.,
RA LaButti K.M., Lechner B.E., Liimatainen K., Lipzen A., Lukacs Z.,
RA Mihaltcheva S., Morgado L.N., Niskanen T., Noordeloos M.E., Ohm R.A.,
RA Ortiz-Santana B., Ovrebo C., Racz N., Riley R., Savchenko A., Shiryaev A.,
RA Soop K., Spirin V., Szebenyi C., Tomsovsky M., Tulloss R.E., Uehling J.,
RA Grigoriev I.V., Vagvolgyi C., Papp T., Martin F.M., Miettinen O.,
RA Hibbett D.S., Nagy L.G.;
RT "Megaphylogeny resolves global patterns of mushroom evolution.";
RL Nat. Ecol. Evol. 3:668-678(2019).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675}.
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DR EMBL; ML213519; TFK48397.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C3MTQ0; -.
DR STRING; 5364.A0A5C3MTQ0; -.
DR Proteomes; UP000305948; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:TFK48397.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000305948}.
FT DOMAIN 170..314
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 572..747
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 746..835
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT REGION 102..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 835..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 383..463
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 857 AA; 95029 MW; 0A1D94DEADDEE45A CRC64;
MPILSSLGWR TVDASPESSG TASVGFTICR EYNRSQTGLA VFCLTYPLLL LDDDWTVSTM
QRTVISRAPL SRIALRRGAT NAIRPASASL WLASRVPRTL TRTYASNPPG GGTGRGGFPG
FSMQPQHQKG DALKEYSVDL TEMAKQGKLD PTIGRDEEIR RTIQILSRRT KSNPVLIGPP
GVGKTAILEG LASRIVAKEV PESLQNKRVL SIDLSAIMAG SGIRGQFEEK FKALIRDIEE
ESRNVICFID EVHTLFNLGK AEGSIDAGQM IKPALARGLQ LVGATTPDEY RKTIEKDAAL
ERRFQPVLID EPTTESTISI LRGLKPRYEV HHGVEISDAA LVTAAVYSAR YISDRFLPDK
AIDLVDEAAS ALRLAQESKP DELEKLDREI VTLQIELESL KNESDTFSTE RRAEVEETLR
KKREESEQLT AIWQAERARL DRIKDLKERL EDAKHELEVS QRQGEYEKAS RLRFAVIPEL
ERQLPKETEM ADDAHESPLA MLHDRVTSND IARVVAKATG IPVQNLLKGE RDKLIHMEDA
LRQRVVGQDH VVSAVSDAVR LSRAGLQPPN RPVASFLFLG PTGVGKTELC KALAAFLYND
EQRGLININM SEYHDRHTMS RLIGAAPGYV GFEEGGQLTE AVRRKPYAVI LLDELEKAHK
DVAMILLQIL DEGSITDSQG RKVDFKNTII CLTSNLGSDI LAHPSASDSN GVVTQQARDE
VLERTSEYFP PELLNRLDSM LVFNKLSRQS ILQVVSLRLR DVADRLKNRR ITLDVDDGAR
EWLAKQGYSD VYGARAIGRV IRTQVLFPLA QKMLNGTIRD GDVVTIRVGG DEKSLHIKDN
HEPDAALGSS TPAVTDN
//
