ID A0A5C4LWK2_9PSEU Unreviewed; 412 AA.
AC A0A5C4LWK2;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE SubName: Full=AI-2E family transporter {ECO:0000313|EMBL:TNC23580.1};
GN ORFNames=FG385_21390 {ECO:0000313|EMBL:TNC23580.1};
OS Amycolatopsis alkalitolerans.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=2547244 {ECO:0000313|EMBL:TNC23580.1, ECO:0000313|Proteomes:UP000305546};
RN [1] {ECO:0000313|EMBL:TNC23580.1, ECO:0000313|Proteomes:UP000305546}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SYSUP0005 {ECO:0000313|EMBL:TNC23580.1,
RC ECO:0000313|Proteomes:UP000305546};
RA Narsing Rao M.P., Li W.J.;
RT "Amycolatopsis alkalitolerans sp. nov., isolated from Gastrodia elata
RT Blume.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TNC23580.1}.
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DR EMBL; VDFW01000019; TNC23580.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C4LWK2; -.
DR OrthoDB; 9784366at2; -.
DR Proteomes; UP000305546; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF75; TRANSPORT PROTEIN SLL0063-RELATED; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000305546};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 54..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 412 AA; 42557 MW; DA9EF4B0B0C3E3A9 CRC64;
MGADNGHAGD GPPPPADTAD APRPATSPDG AAPRPDLRDA AGAVPWRMRV AAALSWRFLL
IIAAVGVIAW VLGYLSAVTI PVGIALLVSA LFAPLVDRLV KWKVPRSLAT LIAIVVGLVA
VGGLLTLVIT TIAASLPQLQ AQLSASLGNI NDWLQRGPLH LSRDQLQQVI DRTIGALRGN
SSELVTRALS TATTIGTTLT QALLALFTLI FFLYGGSQVW NFVLRAVPRG VRAQADVAGR
RGFASLVSYV RATVAVACVD AVCIGIGIWL VGVPLAVPLA AIIFIGAFIP IIGAVAAGTV
AVLVALVANG IVAALIVLAI LIAVMQLESH VLQPFLLGRA VRLHPLAVVL AIAIGVEVSG
IVGALLAVPI LSVIKSAVGS LLHDPELDPA GVNALHPRSA RPQPEQKQPE ND
//
