ID A0A5C5YM66_9BACT Unreviewed; 749 AA.
AC A0A5C5YM66;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Nitrate reductase {ECO:0000313|EMBL:TWT75848.1};
DE EC=1.7.99.4 {ECO:0000313|EMBL:TWT75848.1};
GN Name=narB {ECO:0000313|EMBL:TWT75848.1};
GN ORFNames=Pla123a_26310 {ECO:0000313|EMBL:TWT75848.1};
OS Posidoniimonas polymericola.
OC Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Lacipirellulaceae;
OC Posidoniimonas.
OX NCBI_TaxID=2528002 {ECO:0000313|EMBL:TWT75848.1, ECO:0000313|Proteomes:UP000318478};
RN [1] {ECO:0000313|EMBL:TWT75848.1, ECO:0000313|Proteomes:UP000318478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pla123a {ECO:0000313|EMBL:TWT75848.1,
RC ECO:0000313|Proteomes:UP000318478};
RA Wiegand S., Jogler M., Boedeker C., Pinto D., Vollmers J., Rivas-Marin E.,
RA Kohn T., Peeters S.H., Heuer A., Rast P., Oberbeckmann S., Bunk B.,
RA Jeske O., Meyerdierks A., Storesund J.E., Kallscheuer N., Luecker S.,
RA Lage O.M., Pohl T., Merkel B.J., Hornburger P., Mueller R.-W., Bruemmer F.,
RA Labrenz M., Spormann A.M., Op Den Camp H., Overmann J., Amann R.,
RA Jetten M.S.M., Mascher T., Medema M.H., Devos D.P., Kaster A.-K.,
RA Ovreas L., Rohde M., Galperin M.Y., Jogler C.;
RT "Deep-cultivation of Planctomycetes and their phenomic and genomic
RT characterization uncovers novel biology.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWT75848.1}.
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DR EMBL; SJPO01000006; TWT75848.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C5YM66; -.
DR OrthoDB; 9805142at2; -.
DR Proteomes; UP000318478; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0008940; F:nitrate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 2.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:TWT75848.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000318478}.
FT DOMAIN 57..113
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 749 AA; 83144 MW; 8C42BC6D4CAFCF83 CRC64;
MSHTLTKDSP NDGKARAGLL DTVLSIIHQK DGVLTRDLIR SPGRFGLGQV PDRLKPDATT
DMVCGYCSTG CSLRVHLKEG EAVNLTPTTE YPVNLGMACP KGWEALNVLD ADDRATRPLL
RDASGELKAV SWDKALRTFC DKFKQIGEEH GPESVAFLST GQLVTEEMAL LGSLAKFGMG
MLHGDGNTRQ CMATAATAYK QSFGFDAPPF TYQDFEESDV IVLVGSNLCV AHPIMWERVC
RNPNNPEIIV VDPRRTETAM AATLHLPIRP KSDLAFFYSL AHILCREGWI LRDFVDAHTN
GFDGFAQFVQ AYTPERAAAE SGIPAETIEK VALTIHEGKR VSFWWTMGVN QNYEGVRIAQ
SMINLALMTG NMGRPGAGAN SVTGQCNAMG SRIFSNTTGL LAGRDFLNPT HRQEVADILD
IPVEKLPTEN SLPYHQILEG IRTGTIKGLW VICTNTSHSW IHQSDARDLL EKLDFLVVQD
MYHTTDTAQQ ADLVLPAAGW GEKEGTFINS ERRYGVVKRV RRPPGEALPD FSIFRLVAEY
WGVGEMFRRW ETPEATLGIL KELSRGQPCD ITEIGDYATI DHAGGVQWPC TESPEAIDQQ
RRLFEDGHYY HEDGRAKFLF EDSRAMPEPP DTEYPFLLLT GRGAASQWHT QTRTGKSAVL
RKLYPQGVYV EMNPEDAAIA GLESYDKASV WSRRGELKAT VFVTPTVQPG QLFIPMHYEE
TNRLTLPHFD PYSHQPSYKD CAVAIAPAN
//
