ID A0A5C6AXL1_9BACT Unreviewed; 413 AA.
AC A0A5C6AXL1;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN Name=stp_1 {ECO:0000313|EMBL:TWU04745.1};
GN ORFNames=Pla52n_27880 {ECO:0000313|EMBL:TWU04745.1};
OS Stieleria varia.
OC Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC Stieleria.
OX NCBI_TaxID=2528005 {ECO:0000313|EMBL:TWU04745.1, ECO:0000313|Proteomes:UP000320176};
RN [1] {ECO:0000313|EMBL:TWU04745.1, ECO:0000313|Proteomes:UP000320176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pla52n {ECO:0000313|EMBL:TWU04745.1,
RC ECO:0000313|Proteomes:UP000320176};
RA Wiegand S., Jogler M., Boedeker C., Pinto D., Vollmers J., Rivas-Marin E.,
RA Kohn T., Peeters S.H., Heuer A., Rast P., Oberbeckmann S., Bunk B.,
RA Jeske O., Meyerdierks A., Storesund J.E., Kallscheuer N., Luecker S.,
RA Lage O.M., Pohl T., Merkel B.J., Hornburger P., Mueller R.-W., Bruemmer F.,
RA Labrenz M., Spormann A.M., Op Den Camp H., Overmann J., Amann R.,
RA Jetten M.S.M., Mascher T., Medema M.H., Devos D.P., Kaster A.-K.,
RA Ovreas L., Rohde M., Galperin M.Y., Jogler C.;
RT "Deep-cultivation of Planctomycetes and their phenomic and genomic
RT characterization uncovers novel biology.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001512};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001482};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWU04745.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; SJPN01000003; TWU04745.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C6AXL1; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000320176; Unassembled WGS sequence.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR47992:SF267; ALPHABET, ISOFORM E; 1.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:TWU04745.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000320176}.
FT DOMAIN 4..249
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT DOMAIN 275..390
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 413 AA; 45037 MW; 5946BDDA15FC5DB4 CRC64;
MKTIASAISD RGLKREGNED QYLIDESLGL YLVCDGMGGH AAGEIAAERA IAFAAEYISD
NSDAIESASQ SPEGFYRVLK IAEEAVQNAS QELHLLSKSN IEFAGMGTTM TLLLIVENKA
VMAHVGDSRL YLMRDGDIHQ LSVDHTLANE MYLSGGMTRE EAQASRYQHV LTRSIGAHEF
VPVDTLLFDL IPGDRFLLCS DGLSNYFSDT AVVASLLSEP EIISHPGLLV DFANHSGGSD
NITAVLVDTQ PDTSDPPESN TNTKAKLQCL GNTFLGSRLS VRRLIHLLSI ATTIHCNAGK
EILSRGEKSR GLIVVLKGRF RVDDDDIIES ELTEGDSFGA SSLVMPVESE TILTALEPSQ
VLLIDRRKFH SLTRRLPRLG NALLRNLARH LSEQLAMRGR GRSFNMDDTG PLP
//
