ID A0A5C6HIE9_9BACT Unreviewed; 410 AA.
AC A0A5C6HIE9;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Insulinase family protein {ECO:0000313|EMBL:TWV09894.1};
GN ORFNames=FQ707_13475 {ECO:0000313|EMBL:TWV09894.1};
OS Bacteroidaceae bacterium HV4-6-C5C.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae.
OX NCBI_TaxID=2600309 {ECO:0000313|EMBL:TWV09894.1, ECO:0000313|Proteomes:UP000319088};
RN [1] {ECO:0000313|EMBL:TWV09894.1, ECO:0000313|Proteomes:UP000319088}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HV4-6-C5C {ECO:0000313|EMBL:TWV09894.1,
RC ECO:0000313|Proteomes:UP000319088};
RA Hahnke S., Abendroth C., Pascual J., Langer T., Codoner F.M., Ramm P.,
RA Klocke M., Luschnig O., Porcar M.;
RT "Complete genome sequence of a new Bacteroidaceae bacterium isolated from
RT anaerobic biomass fermentation.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWV09894.1}.
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DR EMBL; VOIU01000027; TWV09894.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C6HIE9; -.
DR OrthoDB; 9811314at2; -.
DR Proteomes; UP000319088; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000319088};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 17..128
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 168..343
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 410 AA; 46921 MW; 23D361CD82634E94 CRC64;
MKINKLTLSN GLRLVHHQDL STQMVALNIL YDVGARDEHP DHTGFAHLFE HLMFGGSVHI
PDYDTPLQQS GGENNAWTNN DITNYYLTIP RSNVEVGFWL ESDRMQELAF SERSLEVQRG
VVMEEFKQRC LNQPYGDVGH LIRALAYQVH PYRWPTIGLD LSHIANAKLE EVKDFFFHFY
APNNAILAVT GNIDWEETVR LAEKWFGPIP AREITPRNLN YEPVQQVEHR QVVERDVPID
ALFMAYHMCE RNSADYYAFD ILSDILSNGR SSRLNQRLVQ ESQLFSSIDA YISGSRDAGL
FHISGKLASG VSLEQAEAAV SNELEQLKNE FIEQAELEKV KNKFESSQIF GNINYLNVAT
NLAWYELTGK AEDIDSEVDE YRAVSAEQLR DVAQRSFVDS NRSVLYYKSK
//
