ID A0A5C6MU70_9TELE Unreviewed; 680 AA.
AC A0A5C6MU70;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=TRMT1-like protein {ECO:0000256|ARBA:ARBA00015939};
GN ORFNames=D4764_07G0011240 {ECO:0000313|EMBL:TWW58405.1};
OS Takifugu flavidus (sansaifugu).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=433684 {ECO:0000313|EMBL:TWW58405.1, ECO:0000313|Proteomes:UP000324091};
RN [1] {ECO:0000313|EMBL:TWW58405.1, ECO:0000313|Proteomes:UP000324091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTHZ2018 {ECO:0000313|EMBL:TWW58405.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TWW58405.1};
RA Xiao S.;
RT "Chromosome genome assembly for Takifugu flavidus.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in motor coordination and exploratory
CC behavior. {ECO:0000256|ARBA:ARBA00003652}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Trm1 family. {ECO:0000256|PROSITE-ProRule:PRU00958}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWW58405.1}.
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DR EMBL; RHFK02000020; TWW58405.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C6MU70; -.
DR Proteomes; UP000324091; Chromosome 7.
DR GO; GO:0160102; F:tRNA (guanine(10)-N2)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007610; P:behavior; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.30.56.70; N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR002905; Trm1.
DR InterPro; IPR042296; tRNA_met_Trm1_C.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR10631; N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10631:SF1; TRMT1-LIKE PROTEIN; 1.
DR Pfam; PF02005; TRM; 2.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51626; SAM_MT_TRM1; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 3: Inferred from homology;
KW Behavior {ECO:0000256|ARBA:ARBA00022610};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; Reference proteome {ECO:0000313|Proteomes:UP000324091};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00958};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU00958};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; tRNA processing {ECO:0000256|PROSITE-ProRule:PRU00958};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 142..169
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 74729 MW; 908A47CD6EF22761 CRC64;
MAELPEVDLA QEDVDIKHGS SGDGGDVAPA VGAPVKEEAA EDAEAKPPTT TTERHISIQT
KLEDLEMLVD LTGAGRKSCP LCPEDKFKAC YSHKLRRHLQ NLHWKVYVEF EGQRMCICHL
PCRHLKNNLS TEQASGRLRA HYHCVVCSVT IARKTDMVSH LKRHVNKGET EASYSGGPDV
LPEDHAPSGH VYEIMKELGT NVQLLPNYST PQKSDTYFNR KMKANRQLVF CSLAVLAQER
NPLECLDAFG ATGIMGLQWA KHLRGAVKVT VNDISEACIK MIKENCKLNN IRVDGGPRGP
RGPDGAGGEA QEVPINSVEV SKMDANVIMH LRPFDYIHLD PYGTAVNYLD AAFRNVRNLG
IISVTSTDTS SLYAKSLNVT LRHYGCQIVR TEYYKELAAR VVIATVARAA ARCNKGIEVL
LAVALEHFVL VVVRVLRGPS QADESAKKLR KLVHCQWCEA RAFLRQGNLA DDTLPCTCHG
SLPGRTALQL GPLWSGPLFN TGFLRQMLLA AVQHNMDDIQ PLVKTLICES ECTTLKSLVH
GAPSLVHGAP ALTNQVECGV VIQTLQSGEE PGAADPPGKR KSGEDSGSIV KRLKLEASLE
HPAFYYSLHR HSIRGMNMPK LNKFLQYLSE AGFRVSRTHF DPTGVRTDAT LEQFKSVLTK
YSVPTCTNSS GTCTSRQSVL
//
