ID A0A5C6MZX1_9TELE Unreviewed; 522 AA.
AC A0A5C6MZX1;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 22-FEB-2023, entry version 11.
DE SubName: Full=Alpha-internexin {ECO:0000313|EMBL:TWW60732.1};
GN ORFNames=D4764_05G0008220 {ECO:0000313|EMBL:TWW60732.1};
OS Takifugu flavidus (sansaifugu).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=433684 {ECO:0000313|EMBL:TWW60732.1, ECO:0000313|Proteomes:UP000324091};
RN [1] {ECO:0000313|EMBL:TWW60732.1, ECO:0000313|Proteomes:UP000324091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTHZ2018 {ECO:0000313|EMBL:TWW60732.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TWW60732.1};
RA Xiao S.;
RT "Chromosome genome assembly for Takifugu flavidus.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWW60732.1}.
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DR EMBL; RHFK02000018; TWW60732.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C6MZX1; -.
DR Proteomes; UP000324091; Chromosome 5.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF13; ZGC:65851; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000324091}.
FT DOMAIN 98..408
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 102..379
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 35..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..490
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..522
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 522 AA; 60009 MW; 26EDE4EA104254A1 CRC64;
MSYSSEMYSS SSYRKIFGDA PRTGRAGLGG SPSRLQSAGY RSSHRSYGSP SMVSSTTYRR
TAAPGRVFSS SSPMQDSMMD LTQSTAITNE LKIVRTNEKE QLQGLNDRFA SFIEKVHNLE
QQNKVLEAEV TVLRQRNNEP SRLHELYEQE IRELRARVEE LTHEKSQMHV DCVQLNDTLE
RLREKLEEES RLREEAENTL KGYRKDVDDA TLARLELEKK VESLLDEIAF LRKVHEEELQ
ELQSSLQASQ VSVEMDMSKP DLAAALKDIR SQYENLSARN QAQAEEWYRS KFVSVTEVAA
RNQDAIKHSK EELSEYRRQV QARTLEIEAL RGHNEALERQ IAEMEDRHNS ELGDMQDTIQ
QLEAALRSTK GEMSRHLREY QDLLNVKMAL DIEIAAYRKL LEGEECRLSA VGGATVQSGY
PGFSYMSSRS YTLGAYRRFA AKPEKEEEEE AEEGEEEEEE EEGEEGEEGD DQEQDEGAEE
EEEEEEEEEK EKEKPNEKKP EEKKEEKKEE KKESPAGKNN KS
//
