ID A0A5C6PHS0_9TELE Unreviewed; 554 AA.
AC A0A5C6PHS0;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Protein phosphatase 1D {ECO:0000313|EMBL:TWW77800.1};
GN ORFNames=D4764_12G0011900 {ECO:0000313|EMBL:TWW77800.1};
OS Takifugu flavidus (sansaifugu).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=433684 {ECO:0000313|EMBL:TWW77800.1, ECO:0000313|Proteomes:UP000324091};
RN [1] {ECO:0000313|EMBL:TWW77800.1, ECO:0000313|Proteomes:UP000324091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTHZ2018 {ECO:0000313|EMBL:TWW77800.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TWW77800.1};
RA Xiao S.;
RT "Chromosome genome assembly for Takifugu flavidus.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU003465}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWW77800.1}.
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DR EMBL; RHFK02000004; TWW77800.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C6PHS0; -.
DR Proteomes; UP000324091; Chromosome 12.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR47992:SF1; PROTEIN PHOSPHATASE 1D; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000324091}.
FT DOMAIN 94..389
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 23..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 473..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..534
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 554 AA; 60947 MW; 34B7FD7786515692 CRC64;
MENTIVARVS VFTDQGGRKY MEDVTEVVVE PEPGEDEPMS EEPEDRRREE GTTSSVTEDE
HDGQTGTEGS SLVSNALCET ARMENADSTV ETVVCGGQSP PGVQPSPAGR SRRSVAFFAV
FDGHGGREAA QFARDYLWEF VKKQRGFWSD YDQEVCSALR KGFVACHHAM WKKLPEWPKT
LTGLPSTSGT TASIVVIRGN RMYVAHVGDS AVVLGVQDDP SLPFIRAVEV TQDHKPELPR
ERERIEGLGG SVIKKSGVNR VVWKRPRLSH NGPVRRSTVI DQIPFLAVAR ALGDLWSYDF
YSGEFVVSPE PDTSVVTLDP KKHRYIVLGS DGLWNMVPPQ EAISMCQNND ETMAPCGVSN
ARQLVSHALL RWRQRMLRAD NTSAIVIALQ EPGVIQDTLN DEEVLLDLSK VSQCPSTPLS
RADTPLLQHS PEEETLATCE LLPALERQDG LSESNRLYRK NLADPFALSP LCPNSSSELP
GQSSPTSRTL GSRTPKSKRT TGGSPSPGRA AKRARCRTAE RPPLVQHNAE KKQKESANVS
TILQRHNKST VCVC
//
