ID A0A5C7GSX5_9ROSI Unreviewed; 533 AA.
AC A0A5C7GSX5;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Low-temperature-induced cysteine proteinase-like {ECO:0008006|Google:ProtNLM};
GN ORFNames=EZV62_026881 {ECO:0000313|EMBL:TXG47587.1};
OS Acer yangbiense.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Sapindaceae; Hippocastanoideae; Acereae; Acer.
OX NCBI_TaxID=1000413 {ECO:0000313|EMBL:TXG47587.1, ECO:0000313|Proteomes:UP000323000};
RN [1] {ECO:0000313|Proteomes:UP000323000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Malutang {ECO:0000313|Proteomes:UP000323000};
RX PubMed=31307060; DOI=10.1093/gigascience/giz085;
RA Yang J., Wariss H.M., Tao L., Zhang R., Yun Q., Hollingsworth P., Dao Z.,
RA Luo G., Guo H., Ma Y., Sun W.;
RT "De novo genome assembly of the endangered Acer yangbiense, a plant species
RT with extremely small populations endemic to Yunnan Province, China.";
RL Gigascience 8:0-0(2019).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TXG47587.1}.
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DR EMBL; VAHF01000013; TXG47587.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C7GSX5; -.
DR Proteomes; UP000323000; Chromosome 13.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 2.10.25.160; Granulin; 1.
DR InterPro; IPR000118; Granulin.
DR InterPro; IPR037277; Granulin_sf.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF950; PROBABLE THIOL PROTEASE-RELATED; 1.
DR Pfam; PF00396; Granulin; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00277; GRAN; 1.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF57277; Granulin repeat; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000323000};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..142
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 172..391
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
FT DOMAIN 427..484
FT /note="Granulins"
FT /evidence="ECO:0000259|SMART:SM00277"
FT REGION 394..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..421
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 59516 MW; 80ABE177C343AC53 CRC64;
MLIVHELTGR PATVSFQFQV STLYIYIYVY KVEYVIKMGS HQLALLFSIL ASLICLSYST
LSSEYSIVGH NFDEIVSEER VVELFQRWKE KHGKVYKHAE EAEKRFMKFK KNLKYVIEKN
ARKNNGHVVG LNKFADMSNE EFKETYLRKV KKPVGKGIDG KARRRKLETC EAPSSLDWRK
KGIVTPVKDQ GSCGSCWSFS TTGAIEGINA LVTGDLISLS EQELVDCDTT NDGCDGGYMD
YAFEWVISNG GIDTEADYPY TSYDGLDGTC NTTKEEFKAV SIDGYEDVDE SDSALYCATV
QQPISVGMDG SAIDFQLYTS GIYDGDCSDN PDDIDHAVLI VGYGSENGED YWIVKNSWGT
SWGMEGYFYI RRNTDLAYGV CAINAMASYP TKESSAPSPY SPPSGVPPPP PPPPPSPPPP
SPSPSECGDY TYCPSGETCC CIFEFFDYCL IYGCCEYDNA VCCTGTEYCC PSDYPVCDIE
EGLCLQNSGD YLGVAAKKRK IAKHKFPWTK FEETKKKYQP LEWKRNPFAA AMR
//
