ID A0A5C8IAN4_9MICO Unreviewed; 445 AA.
AC A0A5C8IAN4;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Glutamine synthetase {ECO:0000313|EMBL:TXK17465.1};
GN ORFNames=FVQ89_11600 {ECO:0000313|EMBL:TXK17465.1};
OS Homoserinibacter sp. GY 40078.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Homoserinibacter.
OX NCBI_TaxID=2603275 {ECO:0000313|EMBL:TXK17465.1, ECO:0000313|Proteomes:UP000321701};
RN [1] {ECO:0000313|EMBL:TXK17465.1, ECO:0000313|Proteomes:UP000321701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GY 40078 {ECO:0000313|EMBL:TXK17465.1,
RC ECO:0000313|Proteomes:UP000321701};
RA Shi S.;
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TXK17465.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; VRTZ01000002; TXK17465.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C8IAN4; -.
DR OrthoDB; 9807095at2; -.
DR Proteomes; UP000321701; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.10.20.70; Glutamine synthetase, N-terminal domain; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR036651; Gln_synt_N_sf.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR PANTHER; PTHR43785; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE; 1.
DR PANTHER; PTHR43785:SF11; GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF03951; Gln-synt_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF54368; Glutamine synthetase, N-terminal domain; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000321701}.
FT DOMAIN 15..100
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 107..445
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 445 AA; 49119 MW; EC39FEED57DA967C CRC64;
MDKQRDFVLR TIEERGVKFV RLWFTDVVGT LKSVALAPAE VEGAFSEGVG IDGSAIEGLT
RASEADVLAH PDPTTFQILP WRGEVDPTAR MFCDITTPDG QPAVADPRNV LKRTLAKAAD
RGFTFYTHPE IEFYLLQSSK LKNGRPVPVD SAGYFDNVPG GTAHDFRRRS VRMLEDLGIS
VEFSHHEAGP GQNEIDLRYA DALTTADNIM TFRTVVKEVA IEQGSYATFM PKPFSEHPGS
GMHTHVSLFE GDANAFFDAG NEYQLSQIGR QFVAGLLRHA PEITAVTNQF VNSYKRLWGG
DEAPSYVTWG HNNRSALVRV PLYKPGKGQS ARVEYRAIDS AANPYLSFSL ILAAGLKGIE
EGYELPAEAD ADVFDMSGAE RRALGYGALP SSLDRALLIM EESELVAETL GEQVFNYVLL
NKRREWAGYR SQVTPFELEA NLEAL
//
