ID A0A5D0CU65_9BACL Unreviewed; 714 AA.
AC A0A5D0CU65;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Formate dehydrogenase subunit alpha {ECO:0000313|EMBL:TYA13412.1};
GN ORFNames=FRY98_12185 {ECO:0000313|EMBL:TYA13412.1};
OS Paenibacillus faecis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=862114 {ECO:0000313|EMBL:TYA13412.1, ECO:0000313|Proteomes:UP000325218};
RN [1] {ECO:0000313|EMBL:TYA13412.1, ECO:0000313|Proteomes:UP000325218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23593 {ECO:0000313|EMBL:TYA13412.1,
RC ECO:0000313|Proteomes:UP000325218};
RA Kook J.-K., Park S.-N., Lim Y.K.;
RT "Genome sequencing of Paenibacillus faecis DSM 23593(T).";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TYA13412.1}.
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DR EMBL; VSDO01000002; TYA13412.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5D0CU65; -.
DR OrthoDB; 9805142at2; -.
DR Proteomes; UP000325218; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0015942; P:formate metabolic process; IEA:InterPro.
DR CDD; cd02753; MopB_Formate-Dh-H; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR041924; Formate_Dh-H_N.
DR InterPro; IPR006478; Formate_DH_asu.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR NCBIfam; TIGR01591; Fdh-alpha; 1.
DR PANTHER; PTHR43105:SF15; FORMATE DEHYDROGENASE H; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 2.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
DR PROSITE; PS00932; MOLYBDOPTERIN_PROK_3; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000325218}.
FT DOMAIN 2..57
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 714 AA; 79096 MW; 98279A091C503A92 CRC64;
MENKVLTVCP YCGSGCQMNL IVEEGKIVGA EPADGRTNEG NLCLKGHYGW DFLNDPQILT
ARIRKPMIRK SGTLAEVSWE EAIQYTAEKL TAIKEKYGPD AIMGTGSARG PGNEANYVMQ
KFMRAVIGTN NVDHCARVCH GPSVAGLTYS LGDGAMSNSI PEIEDTDLLF IFGYNAAVTH
PIVARRIVRA KQKGATIIVI DPRKTESARI ADTWLPLKGG TNMALVNAFG HVLIAEELYD
KQYVEKYVEG FAEYKATVQK YTPEYAESIT GVQAAEIRKV MRQYASANKA MILYGMGVCQ
FAQAVDVVKG LASLALLTGN LGRPGVGIGP VRGQNNVQGS CDMGALPNVY PGYQSVTDDK
IRKKFEKAWG VSLPRKVGYR ITEIPHLVLK EDKVKAYYIF GEDPVQSDPN ASEVRETLDK
LEFVIVQDIF MNKTALHADV IFPATSWGEH DGVYSSADRG FQQIRKAIEP PGEAKPDWQI
ISELATAMGY PMSYRNTEEI WDEMRGLTPS FAGASYRKME EQGSVQWPCP SEDHPGTPYL
YEGNRFTTSS GKGQLFASEW RAPQEQPDQE YPLSLSTVRE VGHYSVRTMT GNCRALSQLS
DEPGFIQMSQ ADASSLGIED GQLVHVVSRR GRVLARAQIS NRVKTGATYM TYHFWIGACN
ELTGDYLDPV SKTPEYKYCA IRIEKIADQL RAEQQVQQEY EALRAQMHVE ARPV
//
