ID A0A5D0NNZ1_9ACTN Unreviewed; 418 AA.
AC A0A5D0NNZ1;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Insulinase family protein {ECO:0000313|EMBL:TYB46187.1};
GN ORFNames=FXF69_12940 {ECO:0000313|EMBL:TYB46187.1};
OS Actinomadura chibensis.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=392828 {ECO:0000313|EMBL:TYB46187.1, ECO:0000313|Proteomes:UP000323380};
RN [1] {ECO:0000313|EMBL:TYB46187.1, ECO:0000313|Proteomes:UP000323380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 14158 {ECO:0000313|EMBL:TYB46187.1,
RC ECO:0000313|Proteomes:UP000323380};
RA Songsumanus A., Kuncharoen N., Kudo T., Yuki M., Igarashi Y.,
RA Tanasupawat S.;
RT "Actinomadura sp. nov. CYP1-5 isolated from mountain soil.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TYB46187.1}.
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DR EMBL; VSFG01000002; TYB46187.1; -; Genomic_DNA.
DR RefSeq; WP_067895231.1; NZ_VSFG01000002.1.
DR AlphaFoldDB; A0A5D0NNZ1; -.
DR STRING; 1220554.GCA_001552135_04767; -.
DR Proteomes; UP000323380; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000323380};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 17..143
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 175..349
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
FT REGION 214..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 44724 MW; E474AF266F5429F1 CRC64;
MAEQPLHEHT LGNGLRVVVC EDHVVPLAAV NIWYGVGSRH ERAGRTGLAH LFEHLMFQGS
ANVAEGEHAA LLESAGAAFN ASTSFERTNY YETVPVSHLE LALWLEADRM GTLPAALTQA
NLDNQRDVVK NERRQRYDNQ PYGTAFERLC DLTFPAGHPY AHTPIGSMED LDATTLEDCA
DFFATWYAPG NAVLSVVGDV DPAKTIEAVE RYFGGLPTGP EKPPTRPGEL GPLSGVREEA
LDEEVPSPAY FAMFTLPTDG GDDVEAAELA VEILGGGSGS RLYDRMVRRD EIATEVWAGV
TRLASGPSLA IVDAIGPEPD KIAAVLDEEL ERFAADGPDA DETARATAQA ERGFLEQTET
VTGLANALSQ NATQFDDPAR VFTAPGRAAA VTGDAIKEMA GRWLAPGART ALTYGGTS
//
