ID A0A5E4ZG80_9BURK Unreviewed; 200 AA.
AC A0A5E4ZG80;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 13-SEP-2023, entry version 12.
DE RecName: Full=thymidylate synthase {ECO:0000256|ARBA:ARBA00011947};
DE EC=2.1.1.45 {ECO:0000256|ARBA:ARBA00011947};
GN ORFNames=PTE30175_05566 {ECO:0000313|EMBL:VVE59647.1};
OS Pandoraea terrae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Pandoraea.
OX NCBI_TaxID=1537710 {ECO:0000313|EMBL:VVE59647.1, ECO:0000313|Proteomes:UP000414233};
RN [1] {ECO:0000313|EMBL:VVE59647.1, ECO:0000313|Proteomes:UP000414233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 30175 {ECO:0000313|EMBL:VVE59647.1,
RC ECO:0000313|Proteomes:UP000414233};
RA Peeters C.;
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CABPRZ010000048; VVE59647.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5E4ZG80; -.
DR Proteomes; UP000414233; Unassembled WGS sequence.
DR GO; GO:0004799; F:thymidylate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd00351; TS_Pyrimidine_HMase; 1.
DR Gene3D; 3.30.572.10; Thymidylate synthase/dCMP hydroxymethylase domain; 1.
DR InterPro; IPR045097; Thymidate_synth/dCMP_Mease.
DR InterPro; IPR023451; Thymidate_synth/dCMP_Mease_dom.
DR InterPro; IPR036926; Thymidate_synth/dCMP_Mease_sf.
DR InterPro; IPR000398; Thymidylate_synthase.
DR NCBIfam; TIGR03284; thym_sym; 1.
DR PANTHER; PTHR11548:SF9; THYMIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11548; THYMIDYLATE SYNTHASE 1; 1.
DR Pfam; PF00303; Thymidylat_synt; 1.
DR PRINTS; PR00108; THYMDSNTHASE.
DR SUPFAM; SSF55831; Thymidylate synthase/dCMP hydroxymethylase; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000414233};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..154
FT /note="Thymidylate synthase/dCMP hydroxymethylase"
FT /evidence="ECO:0000259|Pfam:PF00303"
SQ SEQUENCE 200 AA; 22730 MW; C6F13B500D53421C CRC64;
MKQYLDFMRH VLEHGTEKTD RTGTGTRSVF GYQMRFDLQE GFPLVTTKKL HLKSIIHELL
WFLQGSTNVR YLQENGVTIW NEWADANGEL GPVYGSQWRS WPTPDGGHID QITQLVSQIR
NNPDSRRLIV SAWNVADIPR MKLPPCHVSL TSNRYGQAGK PRQLARSAFS CVRNVINGLV
HHLRPSSSAN EFGQFATAAR
//
