ID A0A5F5XGV0_FELCA Unreviewed; 875 AA.
AC A0A5F5XGV0;
DT 11-DEC-2019, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFCAP00000053401.1};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000053401.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000053401.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000053401.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000053401.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000053401.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000053401.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000053401.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: In the hair cortex, hair keratin intermediate filaments are
CC embedded in an interfilamentous matrix, consisting of hair keratin-
CC associated proteins (KRTAP), which are essential for the formation of a
CC rigid and resistant hair shaft through their extensive disulfide bond
CC cross-linking with abundant cysteine residues of hair keratins. The
CC matrix proteins include the high-sulfur and high-glycine-tyrosine
CC keratins. {ECO:0000256|ARBA:ARBA00003327}.
CC -!- SUBUNIT: Interacts with hair keratins. {ECO:0000256|ARBA:ARBA00011662}.
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DR EMBL; AANG04004523; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A5F5XGV0; -.
DR STRING; 9685.ENSFCAP00000053401; -.
DR Ensembl; ENSFCAT00000077091.1; ENSFCAP00000053401.1; ENSFCAG00000046465.2.
DR GeneTree; ENSGT00940000163441; -.
DR InParanoid; A0A5F5XGV0; -.
DR OMA; CCESVCC; -.
DR Proteomes; UP000011712; Chromosome C2.
DR Bgee; ENSFCAG00000046465; Expressed in tip of external ear and 1 other cell type or tissue.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR InterPro; IPR002494; KAP.
DR PANTHER; PTHR23262; KERATIN ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR23262:SF50; KERATIN-ASSOCIATED PROTEIN 10-4-RELATED; 1.
DR Pfam; PF13885; Keratin_B2_2; 9.
PE 4: Predicted;
KW Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT REGION 1..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..76
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 875 AA; 90446 MW; 7E72183C52381281 CRC64;
MEWTHPTTGL SANGNSASQA LLSGHEPPAT TRHTQGLGDG AANISQEVNQ SASSADTPAI
TRKRKSGGDS GDAQHPREGY KSPWPGAPRP RTCHTHPRPA RLPAQNSSMA DPCCSRTCVI
AASTLSVCSS DLSRGSCVCS PSACTGSSWQ VDSCQESCCE PSCCAPAPCL TLLCGPSSPC
QGDCCTPVCC KPVCCTPVCC KPVCCTPVCC EDSPCTTSSC CQPVCCTPVC CKPVCCTSSP
CQGDCCTPVC CKPVCCTPVC CKPVCCTPVC CKPVCCTPVC CEDSPCTTSS CCQPVCCTSS
PCQGDCCTPV CCKPVCCTPV CCKPVCCKPV CCTPVCCEDS PCSAPSCCQP SPCCRPSSCV
SLLCRPVCRP TCCTPVCCKL FSCTPVCCED SPCTTSSCCQ PSCCTSSPCQ EDCCKPVCCT
PVCCKPVCCT PVCCKPVCCT PVCCKPVCCT PVCCEDSPCT TSSCCQPSCC TSSPCQEDCY
KPVCCTPVRC EDSPCTTSSC CQPSPCCRPS SCVSLLCRPV CRPTCCTPVC CKPVCCTPAC
CKPVCCTPVC CKPVCCTPVC CKPVCCTPAC CKPVCCTPVR CEDSPCTTSS CCQPSCCTSS
PCQEDCYKPV CCTPVCCKPV CCTPACCKPV CCTPVCCKLF SCTPVCCKPV CCTPACCKPV
CCTPACCKPV CCTPVCCEDS PCTTSSCCQP SCCTSSPCQE DCYKPVCCTP VCCKPVCCTP
VCCKPVCCTP ACCKPVCCTP VCCKPVCCTP ACCKPVCCTP VCCEDSPCTT SSCCQPSCCT
SSPCQEDCYK PVCCTPVRCE DSPCTTSSCC QPSPCCRPSS CVSLLCRPVC RPACCAPASS
CRSSCCRPAS CVSLLCRPVC PRPACCGPAS GQSCC
//
