ID A0A5F9CW65_RABIT Unreviewed; 908 AA.
AC A0A5F9CW65;
DT 11-DEC-2019, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=BICD cargo adaptor 2 {ECO:0000313|Ensembl:ENSOCUP00000038032.1};
GN Name=BICD2 {ECO:0000313|Ensembl:ENSOCUP00000038032.1};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000038032.1, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000038032.1, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000038032.1,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000038032.1}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000038032.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BicD family.
CC {ECO:0000256|ARBA:ARBA00010061}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAGW02048247; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02048248; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A5F9CW65; -.
DR SMR; A0A5F9CW65; -.
DR STRING; 9986.ENSOCUP00000038032; -.
DR Ensembl; ENSOCUT00000054440.1; ENSOCUP00000038032.1; ENSOCUG00000010743.3.
DR GeneTree; ENSGT00940000154471; -.
DR InParanoid; A0A5F9CW65; -.
DR Proteomes; UP000001811; Chromosome 1.
DR Bgee; ENSOCUG00000010743; Expressed in blood and 16 other cell types or tissues.
DR GO; GO:0008093; F:cytoskeletal anchor activity; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR Gene3D; 6.10.250.2470; -; 1.
DR InterPro; IPR018477; BICD.
DR PANTHER; PTHR31233; BICAUDAL D FAMILY MEMBER; 1.
DR PANTHER; PTHR31233:SF7; PROTEIN BICAUDAL D HOMOLOG 2; 1.
DR Pfam; PF09730; BicD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 138..165
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 202..344
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 530..589
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 753..872
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 488..507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..701
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 908 AA; 102562 MW; 028D6B9732D4C18C CRC64;
MALRDRPLGA RTNHGRGRAR AGHDGTCRRC GLQSPAFPAR GGAVAARAAV GAGRLRRRRR
RRRWWLRRAR PAAASGEPAR LAATMSAPSE EEEYARLVME AQPEWLRAEL KRLSHELAET
TREKIQAAEY GLAVLEEKHQ LKLQFEELEV DYEAIRSEME QLKEAFGQAH TNHKKVAADG
ESREESLIQE SASKEQYYVR KVLELQTELK QLRNVLTNTQ SENERLTSVA QELKEINQNV
EVQRSRLRDD IKEYKFREAR LLQDYSELEE ENISLQKQVS LLRQNQVEFE GLKHEIKRLE
EEAEYLNSQL EDAIRLKEIS ERQLEEALET LKTEREQKSS LRKELSQYMS INDSFYTSHL
HVSLDGLKFS DDAAAEPNND AEALVNGFEH GLAKPPPDNK TSTPRKDGLA PPSPSLVSDL
LSELHISEIQ KLKQQLVQME REKGGLLVTL QDTQKQLEQA RGALSEQREK VSHLTENLSA
LRRLQAGKER QTALDNEKDR DSHEDGDYYE VDIDGPEVLA CKYHVAVAEA GELREQLRAL
RDTHEAREAQ HAEEKGRYEA EGQALTEKVA LLEKTSRQDR ELLARLEKEL KKVSDVAGET
QGSLSVAQDE LVTFSEELAS LYHHVCMCNN ETPTRVALDY YREGQAGAGR TSPGGRTSPE
GRGRRSPILL SKGLLATEAC RADGGTGDSS PSPSSSLPSP LSDPRREPMN IYNLIAIIRD
QIKHLQAAVD RTTELSRQRI ASQELGPAVD KDKEALMEEI LKLKSLLSTK REQITTLRTV
LKANKQTAEV ALANLKSKYE NEKAMVTETM MKLRNELKAL KEDAATFSSL RAMFATRCDE
YITQLDEMQR QLAAAEDEKK TLNSLLRMAI QQKLALTQRL ELLELDHEQA RRGRAKAAPK
AKPATPSL
//
