ID A0A5J5CT28_9PERO Unreviewed; 1015 AA.
AC A0A5J5CT28;
DT 11-DEC-2019, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAA8582631.1};
DE Flags: Fragment;
GN ORFNames=FQN60_006302 {ECO:0000313|EMBL:KAA8582631.1};
OS Etheostoma spectabile (orangethroat darter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Percoidei; Percidae; Etheostomatinae; Etheostoma.
OX NCBI_TaxID=54343 {ECO:0000313|EMBL:KAA8582631.1, ECO:0000313|Proteomes:UP000327493};
RN [1] {ECO:0000313|EMBL:KAA8582631.1, ECO:0000313|Proteomes:UP000327493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EspeVRDwgs_2016 {ECO:0000313|EMBL:KAA8582631.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAA8582631.1};
RA Moran R.L., Catchen J.M., Fuller R.C.;
RT "A chromosome-level genome assembly, high-density linkage maps, and genome
RT scans reveal the genomic architecture of hybrid incompatibilities
RT underlying speciation via character displacement in darters (Percidae:
RT Etheostominae).";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC12A transporter family.
CC {ECO:0000256|ARBA:ARBA00010593}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA8582631.1}.
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DR EMBL; VOFY01000019; KAA8582631.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5J5CT28; -.
DR Proteomes; UP000327493; Chromosome 19.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR CDD; cd00037; CLECT; 1.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF97; SLC12A10.3 SOLUTE CARRIER FAMILY 12 (SODIUM_POTASSIUM_CHLORIDE TRANSPORTERS), MEMBER 10, TANDEM DUPLICATE 3 ISOFORM X1-RELATED; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 2.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000327493};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 135..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 140..610
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 619..783
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 761..942
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 101..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 757..789
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..786
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1015
FT /evidence="ECO:0000313|EMBL:KAA8582631.1"
SQ SEQUENCE 1015 AA; 113362 MW; 7EBBC6E84F471C8E CRC64;
MGQFTSKRGG VDPRAVPNVR FSGDEGPPSY STHGMPPTIV ISDVESSASE RRGSRVELRR
SSVYSTIDQV PQLGHYTRTL HHQKGSRPSL DALRKAFEEK EAAAEVSTTD SGDGSLPNSG
PEAPKGPPKK APARFGWFIG VMMRCMLNIW GVILFLRVTV ITSQAGIVVM WVIIGLSVMV
TTITGLSISA IATNGRVISG GTYFMISRSL GYELGAPIGL VFSFANALAC ALNTVGFSIV
VRDLMRDYNV IIVDDLNDVR IVGVITLVIL LMITLAGMEW ESKTQILFFI ILLVSFADYL
VGTLIPHSKE KQSKGLFGYN KDIFISNLTP DWRGPDGNFF RMFSIFFPGA TGILSGVNIC
GDLKDPATAI PKGTLGAILV TTLSYLILSV TSGASVVRDA SGNISDYIGG NITSDCVGLG
CNFGWNFTKC ILAQNCKFGL ANTSKCLCKD KIYPYIGFFG KGYGKNNEPL RAYVLCFLIA
VALVIYGDLN TIAALNSNLF MCSYALINFS CFHASITNAP GWRPMFHYYN KWLALFAAAV
AVLLMFLFTW WAALVVLSVM ASLFIYVTYN KPNVNWGSSV QAGSYNMALS YSVALTGVND
HVKNYRPQCL VLTGPPTQRP ALVDFVDSFT KHASLMICGD IIMDRQSQPQ EATDKLVKWM
NKRKVRSFYS SFPADSLRVG ARNLLQTSGL GKLKPNILVL GFKSNWRDSS PESIDDYINT
MYDTFDTNYS LCILRMMEGL DVSDQFDFEV NKGFEPDESI EKDNQKSPQK KPADSIPEED
NKEQMKTVFQ TDQGKKTIDV YWIADDGGLT LLVPYLLTRR KRWHNCKVRV FVVGDEQNME
ENRAEMLKLL DRFRFGFKDV TVMTDSEKRP QAKSLERFEE SVAPFRLYDE QYDGVSAQEL
RENSPWKIPD KEFEAFRQKS ETKVRLNEII RRNSMHAGLV LVEHHQELVS ITNLDQQRSK
KADSLYVWLG LRYTCTLQFW FWVSDEGVCH KNWDSHKTDD VCDTSGAMDR GGQHK
//
