ID   A0A5M6IFI9_9PROT        Unreviewed;       441 AA.
AC   A0A5M6IFI9;
DT   26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2020, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=RsmB/NOP family class I SAM-dependent RNA methyltransferase {ECO:0000313|EMBL:KAA5606495.1};
GN   ORFNames=F1188_06425 {ECO:0000313|EMBL:KAA5606495.1};
OS   Roseospira marina.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Roseospira.
OX   NCBI_TaxID=140057 {ECO:0000313|EMBL:KAA5606495.1, ECO:0000313|Proteomes:UP000324065};
RN   [1] {ECO:0000313|EMBL:KAA5606495.1, ECO:0000313|Proteomes:UP000324065}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15113 {ECO:0000313|EMBL:KAA5606495.1,
RC   ECO:0000313|Proteomes:UP000324065};
RA   Meyer T., Kyndt J.;
RT   "Genome sequence of Roseospira marina, one of the more divergent members of
RT   the non-sulfur purple photosynthetic bacterial family, the
RT   Rhodospirillaceae.";
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RsmB/NOP family. {ECO:0000256|ARBA:ARBA00007494,
CC       ECO:0000256|PROSITE-ProRule:PRU01023}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAA5606495.1}.
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DR   EMBL; VWPJ01000004; KAA5606495.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5M6IFI9; -.
DR   OrthoDB; 9810297at2; -.
DR   Proteomes; UP000324065; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR018314; Fmu/NOL1/Nop2p_CS.
DR   InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR   InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR   InterPro; IPR023267; RCMT.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR22807:SF77; SUN PROTEIN; 1.
DR   Pfam; PF01189; Methyltr_RsmB-F; 1.
DR   PRINTS; PR02008; RCMTFAMILY.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS01153; NOL1_NOP2_SUN; 1.
DR   PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000324065};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU01023};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01023};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}.
FT   DOMAIN          154..439
FT                   /note="SAM-dependent MTase RsmB/NOP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51686"
FT   ACT_SITE        368
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         268
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         295
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         315
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ   SEQUENCE   441 AA;  46517 MW;  AF8C2AFF1B40A9B8 CRC64;
     MTPGARLAAS LDLLTAIAGD PRPADAVAQT FLRARRYIGA GDRRAVTERV YGLLRRHARL
     GWWTGHGTPR DRLIADLVLT DGLTVKAIKA LFSGQGHEPE PLTGPERTLA ERLQGQPLEP
     PEMPEADRLE LPEWLLEPLS ASLSATVGPD WRAALAALNG EAPLDLRVNT LKADREGARA
     ALAEADITAV DGPLAPLALR VEGRVNLAAT APFRDGLVEV QDAGSQVAAA LVGATPGMAV
     CDLCAGAGGK TLALAAAMAG KGRLLACDVS APRLDRAKVR LRRAGVHNAT LHVLDESGRK
     WLKRQAGAFD RVLVDAPCSG TGAWRRNPDA RWRLDPEDLV NLAAEQDAIL VRAARLVRPG
     GRLIYVTCSV LTAENEDRVA AFLTGPAGAG FAPVPVVEAW AEAGLPPDTC PAAGDALSLR
     LVPSVHATDG FFAAVLRRAE E
//