ID   A0A5M6IT63_9PROT        Unreviewed;       306 AA.
AC   A0A5M6IT63;
DT   26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2020, sequence version 1.
DT   27-MAR-2024, entry version 10.
DE   SubName: Full=Dihydrodipicolinate synthase family protein {ECO:0000313|EMBL:KAA5611513.1};
GN   ORFNames=F1189_14400 {ECO:0000313|EMBL:KAA5611513.1};
OS   Rhodovastum atsumiense.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Rhodovastum.
OX   NCBI_TaxID=504468 {ECO:0000313|EMBL:KAA5611513.1, ECO:0000313|Proteomes:UP000325255};
RN   [1] {ECO:0000313|EMBL:KAA5611513.1, ECO:0000313|Proteomes:UP000325255}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21279 {ECO:0000313|EMBL:KAA5611513.1,
RC   ECO:0000313|Proteomes:UP000325255};
RA   Meyer T., Kyndt J.;
RT   "Genome sequence of Rhodovastum atsumiense, a diverse member of the
RT   Acetobacteraceae family of non-sulfur purple photosynthetic bacteria.";
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAA5611513.1}.
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DR   EMBL; VWPK01000020; KAA5611513.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5M6IT63; -.
DR   OrthoDB; 7157803at2; -.
DR   Proteomes; UP000325255; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128:SF67; BLR3884 PROTEIN; 1.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW   Reference proteome {ECO:0000313|Proteomes:UP000325255}.
FT   ACT_SITE        141
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   ACT_SITE        171
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   BINDING         50
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
FT   BINDING         214
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ   SEQUENCE   306 AA;  31948 MW;  111AF99EC916D68A CRC64;
     MMKEALYGGV NAAVLTAMTP DLSVDLDRMA RHCQWLLANG CNGLGILGTT GEANSLGISE
     RISVLEGLAE RGLPPAVMLP GTGTTALTDT VLLTRRAAEL GCRGALLLPP FFYKTPSEDG
     LFAYFSEVIQ RVGGDIRIYL YHFPAQSAVP VTLGLIGRLI KAYPGKVKGV KDSSGDFANT
     KSYVDVFAAD GFEVYCGDDG ALHALLQEGG AGCITAAANV GSAISALVYA NWDRQAGADA
     QVTLSAIRKA VTSAALIPGL KALVARHTGD AGWQAIRPPH LPLSPEARTK LFATFDACGL
     KLTPAG
//