ID A0A5N3X4Y4_MUNRE Unreviewed; 497 AA.
AC A0A5N3X4Y4;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=DM domain-containing protein {ECO:0000259|PROSITE:PS50809};
GN ORFNames=FD755_019748 {ECO:0000313|EMBL:KAB0368714.1};
OS Muntiacus reevesi (Reeves' muntjac) (Cervus reevesi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Cervidae;
OC Muntiacinae; Muntiacus.
OX NCBI_TaxID=9886 {ECO:0000313|EMBL:KAB0368714.1, ECO:0000313|Proteomes:UP000326062};
RN [1] {ECO:0000313|EMBL:KAB0368714.1, ECO:0000313|Proteomes:UP000326062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCam_UCB_Mr {ECO:0000313|EMBL:KAB0368714.1};
RC TISSUE=Fibroblast cell line {ECO:0000313|EMBL:KAB0368714.1};
RA Mudd A.B., Bredeson J.V., Baum R., Hockemeyer D., Rokhsar D.S.;
RT "Discovery of a novel chromosome fission-fusion reversal in muntjac.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00070}.
CC -!- SIMILARITY: Belongs to the DMRT family.
CC {ECO:0000256|ARBA:ARBA00006834}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAB0368714.1}.
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DR EMBL; VCEB01000017; KAB0368714.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N3X4Y4; -.
DR Proteomes; UP000326062; Chromosome 17.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd14417; CUE_DMA_DMRTA1; 1.
DR Gene3D; 4.10.1040.10; DM DNA-binding domain; 1.
DR InterPro; IPR001275; DM_DNA-bd.
DR InterPro; IPR036407; DM_DNA-bd_sf.
DR InterPro; IPR005173; DMA.
DR InterPro; IPR026607; DMRT.
DR InterPro; IPR046472; DMRT5_1_DMB_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR12322; DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT; 1.
DR PANTHER; PTHR12322:SF71; DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A1; 1.
DR Pfam; PF00751; DM; 1.
DR Pfam; PF03474; DMA; 1.
DR Pfam; PF20624; DMRT5_DMB; 1.
DR SMART; SM00301; DM; 1.
DR SUPFAM; SSF82927; Cysteine-rich DNA binding domain, (DM domain); 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS40000; DM_1; 1.
DR PROSITE; PS50809; DM_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00070};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00070};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00070}; Reference proteome {ECO:0000313|Proteomes:UP000326062};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00070}.
FT DOMAIN 89..136
FT /note="DM"
FT /evidence="ECO:0000259|PROSITE:PS50809"
FT DNA_BIND 89..136
FT /note="DM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00070"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 145..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..38
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 52821 MW; 5E95D2D57439AB30 CRC64;
MEQSQCGSRD RSRSGPPHLA PGLVVAAPPP PSPALPVPPG IPVPPTFLRP SSLFLRAAST
AGSGGCLPPA ELESGVGAVA GGYPRTPKCA RCRNHGVVSA LKGHKRFCRW RDCACAKCTL
IAERQRVMAA QVALRRQQAQ EESEARGLQR LLYPGPLGAG ARSSGGSSRT ETSQTASSGP
ATVTALGLSA SRKASGLATP VFEIFQPDYI EEKQGQKESK CDSCESGQEE LGSKSHQFTL
RSSPKSNDVA GKQNIRSSSI SENPNKDDSI QSLHPGEQSG GEESPRSLSS SDLESGNESE
WAKDFTDSTA SHPTVSSRPR DPLDILTKIF PSYRRSRLEG ILQFCKGDVV QAIEEILNGK
ERKPDTRELA NSGPLENTAF PRVSNFSLAG IGFGTLGNKS AFSPLHTTSA SYGSDSSLYS
LNPRLGISPF RLAYSSPGRG LSGFMSPYLT PGLVPALPCR PALDYAFSGV IRDSSYLPIK
DSVTGSRLYS RPNQSNL
//
