ID A0A5N4CQ55_CAMDR Unreviewed; 136 AA.
AC A0A5N4CQ55;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 24-JAN-2024, entry version 10.
DE RecName: Full=Protein S100-A10 {ECO:0000256|ARBA:ARBA00018065};
DE AltName: Full=Calpactin I light chain {ECO:0000256|ARBA:ARBA00033060};
DE AltName: Full=Calpactin-1 light chain {ECO:0000256|ARBA:ARBA00033448};
DE AltName: Full=S100 calcium-binding protein A10 {ECO:0000256|ARBA:ARBA00032653};
GN ORFNames=Cadr_000024813 {ECO:0000313|EMBL:KAB1261027.1};
OS Camelus dromedarius (Dromedary) (Arabian camel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=9838 {ECO:0000313|EMBL:KAB1261027.1, ECO:0000313|Proteomes:UP000299084};
RN [1] {ECO:0000313|EMBL:KAB1261027.1, ECO:0000313|Proteomes:UP000299084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Drom800 {ECO:0000313|EMBL:KAB1261027.1};
RC TISSUE=Blood {ECO:0000313|EMBL:KAB1261027.1};
RX PubMed=30972949; DOI=.1111/1755-0998.13020;
RA Elbers J.P., Rogers M.F., Perelman P.L., Proskuryakova A.A.,
RA Serdyukova N.A., Johnson W.E., Horin P., Corander J., Murphy D.,
RA Burger P.A.;
RT "Improving Illumina assemblies with Hi-C and long reads: an example with
RT the North African dromedary.";
RL Mol. Ecol. Resour. 19:1015-1026(2019).
CC -!- FUNCTION: Because S100A10 induces the dimerization of ANXA2/p36, it may
CC function as a regulator of protein phosphorylation in that the ANXA2
CC monomer is the preferred target (in vitro) of tyrosine-specific kinase.
CC {ECO:0000256|ARBA:ARBA00003539}.
CC -!- SIMILARITY: Belongs to the S-100 family.
CC {ECO:0000256|ARBA:ARBA00007323}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAB1261027.1}.
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DR EMBL; JWIN03000021; KAB1261027.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N4CQ55; -.
DR STRING; 9838.ENSCDRP00005022228; -.
DR Proteomes; UP000299084; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05024; S-100A10; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR028476; S100-A10.
DR InterPro; IPR001751; S100/CaBP7/8-like_CS.
DR InterPro; IPR013787; S100_Ca-bd_sub.
DR PANTHER; PTHR11639:SF74; PROTEIN S100-A10; 1.
DR PANTHER; PTHR11639; S100 CALCIUM-BINDING PROTEIN; 1.
DR Pfam; PF01023; S_100; 1.
DR SMART; SM01394; S_100; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00303; S100_CABP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000299084};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 106..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..83
FT /note="S100/CaBP-9k-type calcium binding subdomain"
FT /evidence="ECO:0000259|SMART:SM01394"
SQ SEQUENCE 136 AA; 15477 MW; CD52B5BDC250E8A0 CRC64;
MVPASLCLVV QTEHTLKENG NCAILESIFQ EEASTDLTKM PSQMEHAMET MMFTFHRFAG
DKGYLTKEDL RVLMEKEFPG FLENQKDPLA VDKIMKDLDQ CRDGKVGFQS FFSLIAGLTI
ACNDYFVVHM KQKGKK
//
