ID A0A5N5SJ13_9CRUS Unreviewed; 146 AA.
AC A0A5N5SJ13;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Histone H4 {ECO:0000256|ARBA:ARBA00020836, ECO:0000256|RuleBase:RU000528};
GN Name=H4_3 {ECO:0000313|EMBL:KAB7494063.1};
GN ORFNames=Anas_07800 {ECO:0000313|EMBL:KAB7494063.1};
OS Armadillidium nasatum.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Peracarida; Isopoda; Oniscidea; Crinocheta;
OC Armadillidiidae; Armadillidium.
OX NCBI_TaxID=96803 {ECO:0000313|EMBL:KAB7494063.1, ECO:0000313|Proteomes:UP000326759};
RN [1] {ECO:0000313|EMBL:KAB7494063.1, ECO:0000313|Proteomes:UP000326759}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANa2 {ECO:0000313|EMBL:KAB7494063.1};
RC TISSUE=Whole body excluding digestive tract and cuticle
RC {ECO:0000313|EMBL:KAB7494063.1};
RX PubMed=31600190; DOI=.1371/journal.pbio.3000438;
RA Becking T., Chebbi M.A., Giraud I., Moumen B., Laverre T., Caubet Y.,
RA Peccoud J., Gilbert C., Cordaux R.;
RT "Sex chromosomes control vertical transmission of feminizing Wolbachia
RT symbionts in an isopod.";
RL PLoS Biol. 17:e3000438-e3000438(2019).
CC -!- FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact
CC DNA into chromatin, limiting DNA accessibility to the cellular
CC machineries which require DNA as a template. Histones thereby play a
CC central role in transcription regulation, DNA repair, DNA replication
CC and chromosomal stability. DNA accessibility is regulated via a complex
CC set of post-translational modifications of histones, also called
CC histone code, and nucleosome remodeling.
CC {ECO:0000256|ARBA:ARBA00002001, ECO:0000256|RuleBase:RU000528}.
CC -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC DNA. {ECO:0000256|RuleBase:RU000528}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the histone H4 family.
CC {ECO:0000256|ARBA:ARBA00006564, ECO:0000256|RuleBase:RU000528}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAB7494063.1}.
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DR EMBL; SEYY01024525; KAB7494063.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N5SJ13; -.
DR Proteomes; UP000326759; Unassembled WGS sequence.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR001951; Histone_H4.
DR InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR PANTHER; PTHR10484; HISTONE H4; 1.
DR PANTHER; PTHR10484:SF0; HISTONE H4; 1.
DR Pfam; PF02969; TAF; 1.
DR PRINTS; PR00623; HISTONEH4.
DR SMART; SM00417; H4; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454, ECO:0000256|RuleBase:RU000528};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU000528};
KW Nucleosome core {ECO:0000256|ARBA:ARBA00023269,
KW ECO:0000256|RuleBase:RU000528};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU000528};
KW Reference proteome {ECO:0000313|Proteomes:UP000326759}.
FT DOMAIN 98..127
FT /note="TATA box binding protein associated factor (TAF)
FT histone-like fold"
FT /evidence="ECO:0000259|Pfam:PF02969"
SQ SEQUENCE 146 AA; 16603 MW; DE7EF9E0397CC457 CRC64;
MVLIEKYFRN LMSLLKSEKA KIFTDTTILY FHIPSKVIPI TRVIQCHGMT IILDHAFPIP
IMGVKSSESG GIILSVVTKV PLANNSGEET RGVLKVFLEN VIRKAVKYTE HAKRKTATAM
DVVYSLKKLG LAYTRRVIYT YHLEYK
//
