ID   A0A5N6DXT4_ASPPA        Unreviewed;       608 AA.
AC   A0A5N6DXT4;
DT   22-APR-2020, integrated into UniProtKB/TrEMBL.
DT   22-APR-2020, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Beta-lactamase-like protein {ECO:0000313|EMBL:KAB8208920.1};
GN   ORFNames=BDV34DRAFT_39351 {ECO:0000313|EMBL:KAB8208920.1};
OS   Aspergillus parasiticus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=5067 {ECO:0000313|EMBL:KAB8208920.1, ECO:0000313|Proteomes:UP000326532};
RN   [1] {ECO:0000313|EMBL:KAB8208920.1, ECO:0000313|Proteomes:UP000326532}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 117618 {ECO:0000313|EMBL:KAB8208920.1,
RC   ECO:0000313|Proteomes:UP000326532};
RG   DOE Joint Genome Institute;
RA   Kjaerbolling I., Vesth T.C., Frisvad J.C., Nybo J.L., Theobald S.,
RA   Kildgaard S., Petersen T.I., Kuo A., Sato A., Lyhne E.K., Kogle M.E.,
RA   Wiebenga A., Kun R.S., Lubbers R.J., Makela M.R., Barry K., Chovatia M.,
RA   Clum A., Daum C., Haridas S., He G., LaButti K., Lipzen A., Mondo S.,
RA   Pangilinan J., Riley R., Salamov A., Simmons B.A., Magnuson J.K.,
RA   Henrissat B., Mortensen U.H., Larsen T.O., De vries R.P., Grigoriev I.V.,
RA   Machida M., Baker S.E., Andersen M.R.;
RT   "Fungal friends and foes A comparative genomics study of 23 Aspergillus
RT   species from section Flavi.";
RL   Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. Type III
CC       sulfatase family. {ECO:0000256|ARBA:ARBA00033751}.
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DR   EMBL; ML734949; KAB8208920.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5N6DXT4; -.
DR   VEuPathDB; FungiDB:BDV34DRAFT_39351; -.
DR   OMA; YTHSHID; -.
DR   Proteomes; UP000326532; Unassembled WGS sequence.
DR   GO; GO:0018741; F:linear primary-alkylsulfatase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0018909; P:dodecyl sulfate metabolic process; IEA:InterPro.
DR   GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR   CDD; cd07710; arylsulfatase_Sdsa1-like_MBL-fold; 1.
DR   Gene3D; 1.25.40.880; Alkyl sulfatase, dimerisation domain; 1.
DR   Gene3D; 3.60.15.30; Metallo-beta-lactamase domain; 1.
DR   Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR   InterPro; IPR038536; Alkyl/aryl-sulf_dimr_sf.
DR   InterPro; IPR029229; Alkyl_sulf_C.
DR   InterPro; IPR029228; Alkyl_sulf_dimr.
DR   InterPro; IPR044097; Bds1/SdsA1_MBL-fold.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR   PANTHER; PTHR43223; ALKYL/ARYL-SULFATASE; 1.
DR   PANTHER; PTHR43223:SF1; ALKYL_ARYL-SULFATASE BDS1; 1.
DR   Pfam; PF14864; Alkyl_sulf_C; 1.
DR   Pfam; PF14863; Alkyl_sulf_dimr; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR   SUPFAM; SSF55718; SCP-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000326532};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          86..306
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   608 AA;  67510 MW;  CBA58DC28AE94BF6 CRC64;
     MTFSPSFSDR ADFDNATRGF IHALKPCIIR NSSGRVVWNN DEYDFLQDAE CPATAEPKLW
     RQGQLNSIQG LFQVADGIYQ IRGFDLSNMT VVEGDKGVIV IDPLTSVECA AAALSLYREH
     RGDRPVTGLI YSHSHVDHFG GAQGVLQPGT STSIPIIAPE GFMAEATSEN IYVGDAMRRR
     AGYMYGMRLP KGPDGHIGCG LGMMPSSGTM SLIPPNVSIC HTGEERTVDG VRIEFQMVPE
     TEAPAEMNFY FPEHKALCIA ECATHCLHNI ITLRGALVRD AKAWARYLDE TAVLYGQKSN
     VLFGGHNWPT WGQDEIVKFI SEQRDLYTYL HDQTVRMMNL GLTGIEIAER FTLPPALQMA
     WHAQGYYGSV SHNVKGIYQR YLGWFDGNPA HLWEYPAAEA GQRYIDCMGG VDEVVRKARK
     YASDGDSRFA VTLLGHVIAS HPEHKESRLA LASVYTKLAY GCENATWRNF YLSGAQDMHS
     PARPDRPEPP KREYRAALSV EQLLTLLSVQ LDGPKAATES FTIDLDLQEQ KESWRLILSN
     GALTYRIKTD HDRSIDTSGL RLTLTKKELV EILNGGRGIR ENSSEGDVSL LFKLMRLVGA
     SVPPASLL
//