ID A0A5N6G1F8_PETAA Unreviewed; 906 AA.
AC A0A5N6G1F8;
DT 22-APR-2020, integrated into UniProtKB/TrEMBL.
DT 22-APR-2020, sequence version 1.
DT 27-MAR-2024, entry version 10.
DE SubName: Full=Rad4 transglutaminase-like domain-containing protein {ECO:0000313|EMBL:KAB8235355.1};
GN ORFNames=BDW43DRAFT_31019 {ECO:0000313|EMBL:KAB8235355.1};
OS Petromyces alliaceus (Aspergillus alliaceus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=209559 {ECO:0000313|EMBL:KAB8235355.1, ECO:0000313|Proteomes:UP000326931};
RN [1] {ECO:0000313|EMBL:KAB8235355.1, ECO:0000313|Proteomes:UP000326931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 536.65 {ECO:0000313|EMBL:KAB8235355.1,
RC ECO:0000313|Proteomes:UP000326931};
RG DOE Joint Genome Institute;
RA Kjaerbolling I., Vesth T., Frisvad J.C., Nybo J.L., Theobald S.,
RA Kildgaard S., Isbrandt T., Kuo A., Sato A., Lyhne E.K., Kogle M.E.,
RA Wiebenga A., Kun R.S., Lubbers R.J., Makela M.R., Barry K., Chovatia M.,
RA Clum A., Daum C., Haridas S., He G., LaButti K., Lipzen A., Mondo S.,
RA Riley R., Salamov A., Simmons B.A., Magnuson J.K., Henrissat B.,
RA Mortensen U.H., Larsen T.O., Devries R.P., Grigoriev I.V., Machida M.,
RA Baker S.E., Andersen M.R.;
RT "Friends and foes A comparative genomics study of 23 Aspergillus species
RT from section Flavi.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
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DR EMBL; ML733071; KAB8235355.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N6G1F8; -.
DR OMA; TWPGKTK; -.
DR OrthoDB; 181129at2759; -.
DR Proteomes; UP000326931; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.60.290; Rad4, beta-hairpin domain BHD2; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000326931}.
FT DOMAIN 526..583
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 585..648
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 655..729
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..906
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..75
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..365
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..784
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..883
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 906 AA; 102311 MW; 2A49D9C62BF360F0 CRC64;
MPPFVPRKRL SSAEPPSAKR HNATAIPSVD IAALDDESDS PLSDVPSEST PQAQETKDEA
GDESGSDDDE VDWEDAMESK ATSATAITPS MTPAHVQDLE LTLDQNEVHL SDIIDGKKAP
SKIERQIRIH SHCLHVQFLL YHNALRNAWA NDSQVHETLR RKLPDALHKE VKKWKVSSGL
ELPEKAPEDT TKEKKKKGKQ RRKPERDWGE GSSRMEPGQP DMSRGDPIIT LLKVLAAFWK
KQFKITAPGL RKHGYRPMSH LEAQISAFNK EEHDPERFGE RVCGVDEFRQ AAERMEGSRD
LGAQLFTALL RALAIEARLV ASLQPLGFGW TKAETSTQKA KVEAEVQTET GEAEDAMDVD
SEDSDSDQDT LKRPNNLKKY DKDLPFPIYW TEVVSPITHQ IIPVDPLVLP NAVATTPELQ
VAFEPRGAKA ERAKQVICYV VAFSSDKTAK DVTTRYLRRR TWPGKTKGYR MPVEKIPVPG
RRGKFYEYNW FRVILRIYER PAKDRTAVDD YEENDLVPNQ PEKKAVKERD TLQSLRASTE
FVLERFLRRE EALKPGSQHV RTFVTGKGNK AKEEKVYRRS DVLKCLSAES WHKEGRQIKK
GEAPLKRVPI RAVTLLRKRE VDELERETGE KPKQGLYAKY QTEYIIPPPI HNGVIPKNDY
GNIDCFVPSM VPRGAAHIPY PGTVRICKKL GIDYAEAVTG FEFGSKMAVP VIEGVVVAAE
NEDLVKDAWR ADAAEKREKE RRKAEARILQ TWRKFLFGLR IAERVREEYG QSSLDHERDV
HNPFTSRRSG QQQACPPVPE PYVHEPSEDE DPVDRGGGFL LPGEHDGDDG GLIVESHQPS
RSVPRPVNEP DEQEIVGEEI PDMSSVQELS SPPQVSASDE QVSDSEPEYA PPTTRRRTRN
VTRKGQ
//
