ID A0A5N6Q794_9ASTR Unreviewed; 574 AA.
AC A0A5N6Q794;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 22-FEB-2023, entry version 8.
DE RecName: Full=MLO-like protein {ECO:0000256|RuleBase:RU280816};
GN Name=MLO {ECO:0000256|RuleBase:RU280816};
GN ORFNames=E3N88_02864 {ECO:0000313|EMBL:KAD7479728.1};
OS Mikania micrantha.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Eupatorieae; Mikania.
OX NCBI_TaxID=192012 {ECO:0000313|EMBL:KAD7479728.1, ECO:0000313|Proteomes:UP000326396};
RN [1] {ECO:0000313|EMBL:KAD7479728.1, ECO:0000313|Proteomes:UP000326396}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NLD-2019 {ECO:0000313|EMBL:KAD7479728.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAD7479728.1};
RA Liu B.;
RT "Mikania micrantha, genome provides insights into the molecular mechanism
RT of rapid growth.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in modulation of pathogen defense and leaf
CC cell death. {ECO:0000256|RuleBase:RU280816}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280816}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU280816}.
CC -!- DOMAIN: The C-terminus contains a calmodulin-binding domain, which
CC binds calmodulin in a calcium-dependent fashion.
CC {ECO:0000256|RuleBase:RU280816}.
CC -!- SIMILARITY: Belongs to the MLO family. {ECO:0000256|ARBA:ARBA00006574,
CC ECO:0000256|RuleBase:RU280816}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAD7479728.1}.
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DR EMBL; SZYD01000001; KAD7479728.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N6Q794; -.
DR Proteomes; UP000326396; Miscellaneous, Linkage group lg1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR InterPro; IPR004326; Mlo.
DR PANTHER; PTHR31942:SF34; MLO-LIKE PROTEIN; 1.
DR PANTHER; PTHR31942; MLO-LIKE PROTEIN 1; 1.
DR Pfam; PF03094; Mlo; 1.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|RuleBase:RU280816};
KW Membrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW ECO:0000256|RuleBase:RU280816};
KW Plant defense {ECO:0000256|RuleBase:RU280816};
KW Reference proteome {ECO:0000313|Proteomes:UP000326396};
KW Transmembrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280816,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 448..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 574 AA; 65601 MW; 587AC9F0997A3F21 CRC64;
MGGASEGRSL EQTPTWAVAI VCFVLVAISI VIEQIIHKIE QWLKKKHNRG LYESLEKIKA
ELMLLGFISL LLTVGTNPIT EICISKRAGS TWHPCSNQKL EQTSNEVAAS ILAGTNIGYN
KCALKGKVSF MSYDGVHQLH IFIFVLAVSH VFYSVITMAL GRLKMGSWKH WETETKSAEY
RFSHDSNRFR FTRDTSFGRR HMSFWSKSPI LLWIVCFYRQ FYRSVPKVDY LTLRHGFIMA
HLTPHSHSGF DFQKYINRSL EEDFKVVVAI SPPIWLFVVA FLLFNTHGLY SYLWLPFIPL
IIVLLVGTKL QVIITKMGLK IQERGEVVKG VPVVHPHDDL FWFNCPRLLL YFINFVLFQV
TLFKFLFYFL MIQCQFGLKS CFHEHMEDVI IRITMGVLIQ ILCSYVTLPL YALVTQMGST
MRPTIFNDRV ASALRKWHHT AKKKIKENKK SGQLTAMPSR PVTPTSSHNL SPVHLLGHYR
NINIDSLDHT SLTRLNLNVM NWNVDGSPNP TNRMIGYSTC HHEIEIGYLD QGMDQVQEPS
LSDVASCSDA ASKTEHEVMV GAPKDSCFEN KPGM
//
