ID A0A5N6SBS6_ASPPS Unreviewed; 1216 AA.
AC A0A5N6SBS6;
DT 22-APR-2020, integrated into UniProtKB/TrEMBL.
DT 22-APR-2020, sequence version 1.
DT 24-JAN-2024, entry version 10.
DE SubName: Full=Amino acid permease-domain-containing protein {ECO:0000313|EMBL:KAE8130853.1};
GN ORFNames=BDV38DRAFT_266036 {ECO:0000313|EMBL:KAE8130853.1};
OS Aspergillus pseudotamarii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=132259 {ECO:0000313|EMBL:KAE8130853.1, ECO:0000313|Proteomes:UP000325672};
RN [1] {ECO:0000313|EMBL:KAE8130853.1, ECO:0000313|Proteomes:UP000325672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 117625 {ECO:0000313|EMBL:KAE8130853.1,
RC ECO:0000313|Proteomes:UP000325672};
RG DOE Joint Genome Institute;
RA Kjaerbolling I., Vesth T., Frisvad J.C., Nybo J.L., Theobald S.,
RA Kildgaard S., Isbrandt T., Kuo A., Sato A., Lyhne E.K., Kogle M.E.,
RA Wiebenga A., Kun R.S., Lubbers R.J., Makela M.R., Barry K., Chovatia M.,
RA Clum A., Daum C., Haridas S., He G., LaButti K., Lipzen A., Mondo S.,
RA Riley R., Salamov A., Simmons B.A., Magnuson J.K., Henrissat B.,
RA Mortensen U.H., Larsen T.O., Devries R.P., Grigoriev I.V., Machida M.,
RA Baker S.E., Andersen M.R.;
RT "Friends and foes A comparative genomics study of 23 Aspergillus species
RT from section Flavi.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ML743691; KAE8130853.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N6SBS6; -.
DR OrthoDB; 5490251at2759; -.
DR Proteomes; UP000325672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF72; GH08340P; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000325672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 162..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 542..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 566..584
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 145..622
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 634..716
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 1149..1212
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 92..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 731..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1009..1132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..746
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1053..1085
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1107..1129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1216 AA; 133369 MW; D8A361085C7F7200 CRC64;
MTHSRDEGTS DSMSRRRPNF STRTAQEDVS RLAPSESPTA SPEENSRFLN WRNALSLRPY
EPLNSSFHTT ERQRHSLPSN FFGSISHWWD KPDNDGPQGT SNRSHLPVDL PTGPLRDSSL
DQKERDGQNY RASDSAAKLG TFSGVFVPTT LNVLSILMFL RFGFILGQAG LLGMLGLLAV
SYTINLVTTM SLSAIATNGT VKGGGAYYLI SRSLGPEFGG SIGIVFYLGY VLNTGMNAVG
LVDCFTQNFG TESGTLSNFL EEGFWWQYLW GTIILLICTG ICLAGSSIFS RASNGLLVIL
LVATFSIPAS AIFMKPFSIP KLHVTFTGVR LQTLLENLKP RLTKGAAGSQ IHGKENFQDL
FGILFPATGG IFAGASMSGD LKNPSHSIPR GTLSGLALTF VTYTLVIVAM AASITRESLY
KNSDIIQMTN ASGIVILLGE FATTFFSALM GVIGSAKLLQ AIARDNLLPG LKIFSKGTKK
NDEPVHAIIV TFVVAQLTML FDINQIASFV TMTYLMTFLV MNLACFLLKI GSAPNFRPSF
HYFNWQTAAA GALVCGATMF FVDGVYATGC VGILILLFLL IHYTSPPKPW GDVSQSLIYH
QVRKYLLRLR QEHVKFWRPQ ILLFVTNLDD QYKMVSFCNS LKKGALFVLG HVIVTDDFSS
AVPEARRQQT TWTKFVENSK VKAFVNIAVS PSAEWGIRNI VLNSGLGGMR PNIVVIDQFR
NGQSLVETIQ PRKDSNDRRD VAPESGVDDV SRPQMSCANY VTILEDLLFK LRINVAVAKG
FENLELPTSG QHQKKYIDLW PIQMSAELGA DSESKKNVLT TNFDTYTLIL QLGCILNTVP
SWKKTYKLRV AVFVEYETDV DDERGRVHAL LEKLRIEAEV LVFWLACGDV KSYRIIVNGD
RSPAVRDMQD RVQTTLKEEG WWQDIEKFRR VSHNQPKSDD LGGELGRVSS WHGASSHDTV
QKAPAQLAGG LKKFIESTRR RRSISSFKGI GGVNLGMQTH RLLDSFVDYD SSDSSSSDSE
LEPYVDDRED GTNNKGLASP DTANHGVPSI VAPATSPKSQ ASGARPPMSR SASSNRFSSS
PIPEAKVNTD EGAGPSIMFA PSSPPPRASN RRESIYTRRS SSVGSGTASG YPRRASVPLS
FNDLPSRAQH LILNELMAEH SNETAVIFTT LPSPMEGTAQ GEAASESYLS DLDVLWQGLP
PCLLVHSNSM TVTMNL
//
