ID A0A5N6T1E3_ASPPS Unreviewed; 568 AA.
AC A0A5N6T1E3;
DT 22-APR-2020, integrated into UniProtKB/TrEMBL.
DT 22-APR-2020, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Phosphatase 2C-like domain-containing protein {ECO:0000313|EMBL:KAE8139903.1};
GN ORFNames=BDV38DRAFT_41915 {ECO:0000313|EMBL:KAE8139903.1};
OS Aspergillus pseudotamarii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=132259 {ECO:0000313|EMBL:KAE8139903.1, ECO:0000313|Proteomes:UP000325672};
RN [1] {ECO:0000313|EMBL:KAE8139903.1, ECO:0000313|Proteomes:UP000325672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 117625 {ECO:0000313|EMBL:KAE8139903.1,
RC ECO:0000313|Proteomes:UP000325672};
RG DOE Joint Genome Institute;
RA Kjaerbolling I., Vesth T., Frisvad J.C., Nybo J.L., Theobald S.,
RA Kildgaard S., Isbrandt T., Kuo A., Sato A., Lyhne E.K., Kogle M.E.,
RA Wiebenga A., Kun R.S., Lubbers R.J., Makela M.R., Barry K., Chovatia M.,
RA Clum A., Daum C., Haridas S., He G., LaButti K., Lipzen A., Mondo S.,
RA Riley R., Salamov A., Simmons B.A., Magnuson J.K., Henrissat B.,
RA Mortensen U.H., Larsen T.O., Devries R.P., Grigoriev I.V., Machida M.,
RA Baker S.E., Andersen M.R.;
RT "Friends and foes A comparative genomics study of 23 Aspergillus species
RT from section Flavi.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU003465}.
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DR EMBL; ML743564; KAE8139903.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N6T1E3; -.
DR OrthoDB; 11028at2759; -.
DR Proteomes; UP000325672; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR13832:SF876; PROTEIN PHOSPHATASE 1G; 1.
DR PANTHER; PTHR13832; PROTEIN PHOSPHATASE 2C; 1.
DR Pfam; PF00481; PP2C; 2.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000325672}.
FT DOMAIN 139..468
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..541
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..568
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 60604 MW; A8EEE162009B6E84 CRC64;
MFSGSSSPPK DKSNSVPHSG AVDTQSLSVH PEEGGVTHTS KSLPSGGFFT RRTSEDQGPA
GEKKRRSSTV TKAATFFTNA KNSLSLSSSP RESSSFNYTV RSPQTLQSLG SMDPALSVPQ
GSLNNSAGDS LPTPRSSFKV GVTEDRNRKC RRTMEDTHAY LYNFLGTPAP LARADGENQL
GSSLTPVEAS SVVETDNGYF AIFDGHAGTF AAEWCGKKLH LILEDIMKKN PNTPVPELLD
QTFTSVDQQL EKLPVKNSGC TAVIALLRWE DRIPSSHSAT GSSALAPAAA AAAKGDSTSE
ADDTPTQATS TGPSILPKLQ EKAIRQRVLY TANVGDARII LCRNGKALRL SYDHKGSDEN
EGKRIANAGG LILNNRVNGV LAVTRALGDA YLKDLVTGHP YTTETVVQPD SDEFIILACD
GLWDVCTDQE AVDLVRNVPD AQEASKILVD YALARFSTDN LSCMVIRLDT DRVKEVINKT
AEPIGVAGDP SMDVEHGVSE ADKIIEGARK SMANTDIADD SEAAEKVKDE ILHKMADGEP
GPEMSVDDSN DAPTVSHLNK SDANNGNP
//
