ID A0A5N8YPR0_9CHLR Unreviewed; 362 AA.
AC A0A5N8YPR0;
DT 22-APR-2020, integrated into UniProtKB/TrEMBL.
DT 22-APR-2020, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=ACR3 family arsenite efflux transporter {ECO:0000313|EMBL:MQF67493.1};
GN Name=arsB {ECO:0000313|EMBL:MQF67493.1};
GN ORFNames=FIM07_03525 {ECO:0000313|EMBL:MQF67493.1};
OS SAR202 cluster bacterium AD-802-F09_MRT_200m.
OC Bacteria; Chloroflexota; SAR202 cluster.
OX NCBI_TaxID=2587839 {ECO:0000313|EMBL:MQF67493.1, ECO:0000313|Proteomes:UP000327232};
RN [1] {ECO:0000313|EMBL:MQF67493.1, ECO:0000313|Proteomes:UP000327232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AD-802-F09_MRT_200m {ECO:0000313|EMBL:MQF67493.1};
RA Saw J.H., Nunoura T., Hirai M., Takaki Y., Parsons R., Michelsen M.,
RA Longnecker K., Kujawinski E.B., Stepanauskas R., Landry Z., Carlson C.A.,
RA Giovannoni S.J.;
RT "Pangenomics reveal diversification of enzyme families and niche
RT specialization in globally abundant SAR202 bacteria.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|PIRNR:PIRNR005508}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|PIRNR:PIRNR005508}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC family. {ECO:0000256|ARBA:ARBA00010110, ECO:0000256|PIRNR:PIRNR005508}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MQF67493.1}.
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DR EMBL; VEXI01000025; MQF67493.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N8YPR0; -.
DR Proteomes; UP000327232; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR004706; Arsenical-R_Acr3.
DR InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR NCBIfam; TIGR00832; acr3; 1.
DR PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR Pfam; PF01758; SBF; 1.
DR PIRSF; PIRSF005508; Acr3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR005508};
KW Membrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000327232};
KW Transmembrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|PIRNR:PIRNR005508,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR005508}.
FT TRANSMEM 26..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 362 AA; 39710 MW; 825F77D6ACE79BAA CRC64;
MASFPTSEPL GPSSIGFDRL SPLDRYLTIW IFLAMAIGVA SGHFWPSISD FTGSLTVGST
SIPIAIGLIL MMYPPLAKVR YEELGEVFRN WKILILSLTQ NWLIGPVLMF LLAIVFLRDH
PEFMAGVILI GTARCIAMVL IWNELAKGDS QYAAGLVALN SIFQILFYSA YAFIFITVLP
PWFGLEGLEV DITITEIAKS VAIYLGIPFF AGILSRTLLI RAMGRLWFER VFIPRISPLT
LIALIFTILV MFSLKGNVIV DIPLDVVRIA IPLSIYFVVM FLISFYMGKS MGVDYSKTTA
VALTAASNNF ELAIAVAVGV FGIGSGQALA AVVGPLVEVP VLIGLVNVAL YFQRRFFMRA
VA
//
