ID A0A5Q0UGE9_9ARCH Unreviewed; 364 AA.
AC A0A5Q0UGE9;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=tRNA (guanine(26)-N(2))-dimethyltransferase {ECO:0000256|ARBA:ARBA00039099};
DE EC=2.1.1.216 {ECO:0000256|ARBA:ARBA00039099};
GN Name=trm1 {ECO:0000313|EMBL:QGA80722.1};
GN ORFNames=LC1Nh_0838 {ECO:0000313|EMBL:QGA80722.1};
OS Candidatus Nanohalobium constans.
OC Archaea; Candidatus Nanohaloarchaeota; Candidatus Nanohalobia;
OC Candidatus Nanohalobiales; Candidatus Nanohalobiaceae;
OC Candidatus Nanohalobium.
OX NCBI_TaxID=2565781 {ECO:0000313|EMBL:QGA80722.1, ECO:0000313|Proteomes:UP000377803};
RN [1] {ECO:0000313|Proteomes:UP000377803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC1Nh {ECO:0000313|Proteomes:UP000377803};
RA La Cono V., Arcadi E., Crisafi F., Denaro R., La Spada G., Messina E.,
RA Smedile F., Toshchakov S.V., Shevchenko M.A., Golyshin P.N.,
RA Golyshina O.V., Ferrer M., Rohde M., Mushegian A., Sorokin D.Y.,
RA Giuliano L., Yakimov M.M.;
RT "Candidatus Nanohalobium constans, a novel model system to study the DPANN
RT nano-sized archaea: genomic and physiological characterization of a
RT nanoarchaeon co-cultured with its chitinotrophic host.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Trm1 family. {ECO:0000256|PROSITE-ProRule:PRU00958}.
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DR EMBL; CP040089; QGA80722.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5Q0UGE9; -.
DR KEGG; ncon:LC1Nh_0838; -.
DR OrthoDB; 372177at2157; -.
DR Proteomes; UP000377803; Chromosome.
DR GO; GO:0160102; F:tRNA (guanine(10)-N2)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0160104; F:tRNA (guanine(26)-N2)-dimethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0160103; F:tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR Gene3D; 3.30.56.70; N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR002905; Trm1.
DR InterPro; IPR042296; tRNA_met_Trm1_C.
DR NCBIfam; TIGR00308; TRM1; 1.
DR PANTHER; PTHR10631; N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10631:SF3; TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE; 1.
DR Pfam; PF02005; TRM; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51626; SAM_MT_TRM1; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; Reference proteome {ECO:0000313|Proteomes:UP000377803};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00958};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU00958};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; tRNA processing {ECO:0000256|PROSITE-ProRule:PRU00958};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555, ECO:0000256|PROSITE-
KW ProRule:PRU00958}.
SQ SEQUENCE 364 AA; 41780 MW; A3FBEBB77B090EC2 CRC64;
MEKGEERGVK FYSSKEAEMD TEVFFNKEMR TNRDLSAIAA KVYSRKIDEE MRICDALAAS
GIRGMRYTDS GKVWMNDANP SAIEAMKKGL EENDLDAEVS EQDTNVFLSQ SKNFYHFVDI
DPYGSFVNFL DSAARATHHN GFAGFSATDN AAPAGSYPTV CQRRYGSKPL KNSFMHETGL
RIYLKEVFEN YARYDKAFDP KICWHERHYT RIMGRVTESK QRCNNSLENI GYISHCSNCG
WRKLERIDEC PRCETETQKA GPLWIGKIAD RRFTQEMLKE IPEEWEDSVE LLEKVHGEAE
IVTPYYDIHE LCSKHKLQVP KLEEVIESLE QTGYPVSPTH FCPTGIRTDA PLDDVLDIIK
IQSE
//
