ID A0A5R9EHR3_9LACT Unreviewed; 381 AA.
AC A0A5R9EHR3;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 27-MAR-2024, entry version 10.
DE SubName: Full=AI-2E family transporter {ECO:0000313|EMBL:TLQ48833.1};
GN ORFNames=FEZ33_03425 {ECO:0000313|EMBL:TLQ48833.1};
OS Ruoffia tabacinasalis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Ruoffia.
OX NCBI_TaxID=87458 {ECO:0000313|EMBL:TLQ48833.1, ECO:0000313|Proteomes:UP000306420};
RN [1] {ECO:0000313|EMBL:TLQ48833.1, ECO:0000313|Proteomes:UP000306420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FAM 24227 {ECO:0000313|EMBL:TLQ48833.1,
RC ECO:0000313|Proteomes:UP000306420};
RA Roder T., Wuthrich D., Sattari Z., Von Ah U., Bar C., Ronchi F.,
RA Macpherson A.J., Ganal-Vonarburg S.C., Bruggmann R., Vergeres G.;
RT "The metagenome of a microbial culture collection derived from dairy
RT environment covers the genomic content of the human microbiome.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TLQ48833.1}.
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DR EMBL; VBSP01000007; TLQ48833.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5R9EHR3; -.
DR OrthoDB; 9793390at2; -.
DR Proteomes; UP000306420; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF75; TRANSPORT PROTEIN SLL0063-RELATED; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 381 AA; 43196 MW; FDE53CD19F02A36A CRC64;
MDKLGRLDRM VMKYVILAAV FILVIFNYQH IFAGLRELWD IISPVVYGFV FAYILNLIMV
MYEGFWFPET DNELLIRARR PVSILLALIT VIIVIVLVLW LIIPQLISLV QTLLENLPLM
VEYIQRWIED LEEIYPQIDT LINNLNINWE SIARDAASFA NNILGSTFTT FQLLTSSLFR
LVVILVVAIY ALFSKEKIQR QVKRVLRAYM KRDHFRRLKY VLRVTNESFS SFITGMLIEA
IIYGTLVTVG MMIFNFPYAG MIGALSGALA LVPMVGAILS AVIGTMLVFV QNPIQGLFFL
LFNIVLQQLE SNAIYPRIVG GSIGLPGIWT FIAVTIGGGI LGPAGFFLGV PIASVIYKLI
RSNVEYKEHY YELDHGSELT F
//
