ID A0A5S3P2P1_9SPHN Unreviewed; 412 AA.
AC A0A5S3P2P1;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=RsmB/NOP family class I SAM-dependent RNA methyltransferase {ECO:0000313|EMBL:TMM47131.1};
GN ORFNames=FEV51_10070 {ECO:0000313|EMBL:TMM47131.1};
OS Qipengyuania marisflavi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Qipengyuania.
OX NCBI_TaxID=2486356 {ECO:0000313|EMBL:TMM47131.1, ECO:0000313|Proteomes:UP000309668};
RN [1] {ECO:0000313|EMBL:TMM47131.1, ECO:0000313|Proteomes:UP000309668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KEM-5 {ECO:0000313|EMBL:TMM47131.1,
RC ECO:0000313|Proteomes:UP000309668};
RA Yoon J.-H.;
RT "Erythrobacter marisflavi sp. nov., isolated from isolated from water of an
RT estuary environment.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|ARBA:ARBA00007494,
CC ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TMM47131.1}.
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DR EMBL; VCAO01000005; TMM47131.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5S3P2P1; -.
DR OrthoDB; 9810297at2; -.
DR Proteomes; UP000309668; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.10.940.10; NusB-like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018314; Fmu/NOL1/Nop2p_CS.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22807:SF61; NOL1_NOP2_SUN FAMILY PROTEIN _ ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR Pfam; PF01029; NusB; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR SUPFAM; SSF48013; NusB-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01153; NOL1_NOP2_SUN; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000309668};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}.
FT DOMAIN 130..411
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT ACT_SITE 349
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 233..239
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 254
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 280
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 296
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 412 AA; 44482 MW; E90BE450583E8EB1 CRC64;
MAQPPGIHAR RAALRILDAV MRRGDTLDTA FGAATKDVRK FEDKALTRAI ASEVLRWLTD
LDTLIDSATK TNLPPDAKPR MVLRMMLAQW LRLDTPPHAV LATGLPLLAG GPRRLAHGVF
STLAKREVTL PDAPTLPAEV SERWGERAAA IAAGLAHPPP LDLELRDSAE TVQWANQLAG
DSLMPGHIRL PRGSAIEKLP GFADGAWWVQ DLAASLPARL LGPGEARHAL DLCAAPGGKT
LQLAAAGWNV TALDISKRRL ELLRDNLKRT DLKAGIVRAD ALGWEPKHQF DAILLDAPCT
ATGTARRHPD VLHRIGPRQI AEMAELQTAL LERAQSWLKP GGVLIYAVCS LEPEEGEQQA
QRVTLGPLPI TADELPAGLS PTAEGWLRTD PGMLTEQGGL DGFFIARWRA PG
//
